Accurate and reliable measurements of exposure to tobacco products are essential for
identifying and confirming patterns of tobacco product use and for assessing their potential …

There are established guidelines for bioanalytical assay validation and qualification of
biomarkers. In this review, they were applied to a panel of urinary biomarkers of tobacco …

We developed and applied high throughput liquid and gas chromatography–tandem mass
spectrometry (LC-MS/MS and GC-MS/MS) methods for the cigarette smoking-associated …

ABSTRACT A liquid chromatography tandem mass spectrometry (LC/MS/MS) method was
developed and validated for the determination of five total tobacco‐specific N‐nitrosamines …

Mass spectrometry-based proteomics methodology has become an important tool in
elucidating some of the underlying mechanisms involved in cardiovascular disease. The …

Renal cell carcinomas (RCCs) are among the highest causes of cancer mortality. Although
transcriptome profiling studies in the last decade have made significant molecular findings …

Background: Absolute quantification of protein biomarkers such as serum apolipoprotein A1
by both immunoassays and LC–MS can provide misleading results. Results: Recombinant …

Objective: Cancer mortality inequity among persons of African Ancestry is remarkable. Yet,
Black inclusion in cancer biology research is sorely lacking and warrants urgent attention …

Background/Aims: Excretion of urinary compounds in spot urine is often estimated relative to
creatinine. For the growing number of liquid chromatography-tandem mass spectrometry …

Tobacco‐specific N‐nitrosamines (TSNAs), including N′‐nitrosonornicotine, 4‐
(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanone, N′‐nitrosoanatabine, and N …