Non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH) has become the leading
cause of liver disease worldwide. NASH, an advanced form of NAFL, can be progressive …

The most prevalent diseases of our time, non-communicable diseases (NCDs)(including
obesity, type 2 diabetes, cardiovascular diseases and some types of cancer) are rising …

The gut microbiota is a complex and plastic consortium of microorganisms that are intricately
connected with human physiology. The liver is a central immunological organ that is …

Background Although microbioa‐based therapies have shown putative effects on the
treatment of non‐alcoholic fatty liver disease (NAFLD), it is not clear how microbiota‐derived …

The prevalence of nonalcoholic fatty liver disease (NAFLD) has been significantly increased
due to the global epidemic of obesity. The disease progression from simple steatosis (NAFL) …

Farnesoid X receptor (FXR) is a nuclear receptor for bile acids (BAs) that is widely
expressed in the intestine, liver and kidney. FXR has important regulatory impacts on a wide …

Inflammatory bowel diseases, principally Crohn's disease and ulcerative colitis, are
multifactorial chronic conditions. Alterations in gut microbial patterns partly affect disease …

Bile acids are amphipathic, detergent molecules. The detergent effects of di-α-hydroxy-bile
acids are relevant to several colonic diseases. The aims were to review the concentrations …

Obesity, a chronic metabolic disorder caused by an energy imbalance, has been
increasingly prevalent and poses a global health concern. The multifactorial etiology of …

Background & aim Non-alcoholic steatohepatitis (NASH) is a severe form of non-alcoholic
fatty liver disease (NAFLD) that is responsible for a growing fraction of cirrhosis and liver …