Osteoporosis is a highly prevalent disorder characterized by low bone mineral density and
an increased risk of fracture, termed osteoporotic fracture. Notably, bone mineral density …

Osteoporosis and fracture risk are common complex diseases, caused by an interaction of
numerous disease susceptibility genes and environmental factors. With the advances in …

Osteoporosis is a common aging-related disease diagnosed primarily using bone mineral
density (BMD). We assessed genetic determinants of BMD as estimated by heel quantitative …

Background Recently, the association between inflammatory bowel disease (including
ulcerative colitis and Crohn's disease) and BMD has attracted great interest in the research …

INTRODUCTION White matter in the human brain serves a critical role in organizing
distributed neural networks. Diffusion magnetic resonance imaging (dMRI) has enabled the …

Osteoporotic fracture is among the most common and costly of diseases. While reasonably
heritable, its genetic determinants have remained elusive. Forearm fractures are the most …

Wnt signaling executes an indispensable performance in osteoblast differentiation, bone
development, homeostasis, and remodeling. Wnt signals trigger the intracellular Wnt …

Osteoporosis is a devastating disease with an essential genetic component. GWAS have
discovered genetic signals robustly associated with bone mineral density (BMD), but not the …

Although snoring is common in the general population, its aetiology has been largely
understudied. Here we report a genetic study on snoring (n~ 408,000; snorers~ 152,000) …

Skull bone mineral density (SK-BMD) provides a suitable trait for the discovery of key genes
in bone biology, particularly to intramembranous ossification, not captured at other skeletal …