The burgeoning organic near-infrared (NIR) ratiometric small-molecule fluorescent probes
with excellent merits have attracted great attention over the past few years. The traditional …

Adenosine is an evolutionary ancient metabolic regulator linking energy state to physiologic
processes, including immunomodulation and cell proliferation. Tumors create an adenosine …

Ectonucleotidases are key for purinergic signaling. They control the duration of activity of
purinergic receptor agonists. At the same time, they produce hydrolysis products as …

Alkaline phosphatases (ALPs) are a group of isoenzymes located on the outer layer of the
cell membrane. They catalyze the hydrolysis of organic phosphate esters found in the …

Alkaline phosphatase (ALP) that is a crucial biomarker for the diagnosis of hepatobiliary and
skeletal diseases is widely distributed in human bone, liver, intestine, placenta and other …

Zinc, an essential micronutrient in the human body, is a component in over 300 enzymes
and participates in regulating enzymatic activity. Zinc metalloenzymes play a crucial role in …

The Mediterranean diet (MD) has been recommended for type 2 diabetes (T2D) treatment.
The impact of diet in sha** the gut microbiota is well known, particularly for MD. However …

Tissue-nonspecific alkaline phosphatase (TNAP) is a key enzyme responsible for skeletal
tissue mineralization. It is involved in the dephosphorylation of various physiological …

Simple Summary This review provides a comprehensive summary of the literature published
thus far to highlight the prognostic significance of serum albumin (ALB) level and various …

Heterocycles are a class of compounds that have been found to be potent inhibitors of
alkaline phosphatase (AP), an enzyme that plays a critical role in various physiological …