RNAs are involved in the crucial processes of disease progression and have emerged as
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …

DNA nanotechnology is a unique field, where physics, chemistry, biology, mathematics,
engineering, and materials science can elegantly converge. Since the original proposal of …

As CASP15 participants, in the new category of 3D RNA structure prediction, we applied
expert modeling with the support of our proprietary system RNAComposer. Although …

RNA origami is a method for designing RNA nanostructures that can self-assemble through
co-transcriptional folding with applications in nanomedicine and synthetic biology. However …

RNA nanotechnology aims to use RNA as a programmable material to create self-
assembling nanodevices for application in medicine and synthetic biology. The main …

Cryogenic electron microscopy (cryo-EM) is a promising method for characterizing the
structure of larger RNA structures and complexes. However, the structure of individual …

DNA origami enables the creation of complex 3D shapes from genetic material. Future uses
could include the delivery of genetic instructions to cells, but nuclear import remains a major …

Recent discoveries in biology have highlighted the importance of protein and RNA-based
condensates as an alternative to classical membrane-bound organelles. Here, we …

Hybrid RNA: DNA origami, in which a long RNA scaffold strand folds into a target
nanostructure via thermal annealing with complementary DNA oligos, has only been …

Identifying RNA transcript isoforms requires intricate protocols that suffer from various
enzymatic biases. Here we design three-dimensional molecular constructs that enable …