Human leukocyte antigen (HLA) and immune regulation: how do classical and non-classical HLA alleles modulate immune response to human immunodeficiency …

NB Crux, S Elahi - Frontiers in immunology, 2017 - frontiersin.org
The genetic factors associated with susceptibility or resistance to viral infections are likely to
involve a sophisticated array of immune response. These genetic elements may modulate …

Deciphering the role of mucosal immune responses and the cervicovaginal microbiome in resistance to HIV infection in HIV-exposed seronegative (HESN) women

S Munusamy Ponnan, K Thiruvengadam… - Microbiology …, 2021 - Am Soc Microbiol
The female genital tract (FGT) is an important site of human immunodeficiency virus (HIV)
infection. Discerning the nature of HIV-specific local immune responses is crucial for …

KIR2DL5B and HLA DRB1* 12 alleles seems to be associated with protection against HIV‐1 in serodiscordant couples in Burkina Faso

TD Lallogo, FW Djigma, PA Sorgho… - Journal of Medical …, 2022 - Wiley Online Library
The human immunodeficiency virus (HIV) belongs to the Retroviridae family and remains a
public health problem in sub‐Saharan Africa. Recent reports from WHO have shown that 33 …

Role of Killer cell immunoglobulin-like receptors (KIR) genes in stages of HIV-1 infection among patients from Burkina Faso

PA Sorgho, FW Djigma, JJ Martinson, AT Yonli… - Biomolecular …, 2019 - degruyter.com
Objectives A cluster of specialized KIR genes of specialized KIR genes has been shown to
be associated with susceptibility or resistance to viral infections in humans. Therefore, this …

Inhibitory natural killer cell receptor KIR3DL1 with its ligand Bw4 constraints HIV-1 disease among South Indians

S Maruthamuthu, R Rajalingam, K Pandian… - Aids, 2018 - journals.lww.com
Objective: To investigate the role of genotypic and phenotypic characteristics of killer cell
immunoglobulin-like receptors (KIRs) and their human leukocyte antigen (HLA) class-1 …

Killer‐Cell Immunoglobulin‐Like Receptors (KIR) in HIV‐Exposed Infants in Cameroon

KS Luc-Aimé, Y Louis-Marie, LE Gabriel… - Journal of …, 2021 - Wiley Online Library
The biological reason (s) behind persistent mother‐to‐child transmission (MTCT) of HIV
(albeit at reduced rate compared to the preantiretroviral therapy era) in spite of the …

[HTML][HTML] Insights into the interplay between KIR gene frequencies and chronic HBV infection in Burkina Faso

PA Sorgho, JJ Martinson, FW Djigma… - … of Hematology and …, 2018 - ncbi.nlm.nih.gov
Methods Chronic HBV carriers and healthy patients were selected for this study. The viral
load for HBV were performed, and SSP-PCR was used to characterize the frequencies of …

An assessment of toll-like receptor 7 and 8 gene polymorphisms with susceptibility to HIV-1 infection, AIDS development and response to antiretroviral therapy

I Zaidane, A Ouladlahsen, R Bensghir, H Chihab… - Immunology …, 2020 - Elsevier
Toll-like receptors (TLRs) play an important role in activating the innate immune response,
inducing inflammation and initiating the adaptive immune response. In this study, we assess …

Killer immunoglobulin-like receptor 2DS5 is associated with recovery from coronavirus disease 2019

V Lesan, M Bewarder, C Metz, A Becker… - Intensive Care Medicine …, 2021 - Springer
Background Despite numerous advances in the identification of risk factors for the
development of severe coronavirus disease 2019 (COVID-19), factors that promote recovery …

Expression of Killer Immunoglobulin Receptor Genes among HIV‐Infected Individuals with Non‐AIDS Comorbidities

FF Abou Hassan, M Bou Hamdan… - Journal of …, 2022 - Wiley Online Library
Combined antiretroviral therapy (cART) increased the life expectancy of people living with
HIV (PLHIV) and remarkably reduced the morbidity and mortality associated with HIV …