Association between obesity, inflammation and insulin resistance: Insights into signaling pathways and therapeutic interventions

SS Garg, K Kushwaha, R Dubey, J Gupta - Diabetes research and clinical …, 2023 - Elsevier
Obesity, a metabolic disorder, is becoming a worldwide epidemic that predominantly
increases the risk for various diseases including metabolic inflammation, insulin resistance …

Recent advances in nanomedicines for regulation of macrophages in wound healing

A Joorabloo, T Liu - Journal of nanobiotechnology, 2022 - Springer
Macrophages are essential immune cells and play a major role in the immune response as
pro-inflammatory or anti-inflammatory agents depending on their plasticity and functions …

Increased phagocytosis in the presence of enhanced M2-like macrophage responses correlates with increased primary and latent HSV-1 infection

U Jaggi, M Yang, HH Matundan, S Hirose… - PloS …, 2020 - journals.plos.org
After HSV-1 infection, macrophages infiltrate early into the cornea, where they play an
important role in HSV-1 infection. Macrophages are divided into M1 or M2 groups based on …

The MHC class II antigen presentation pathway in human monocytes differs by subset and is regulated by cytokines

J Lee, H Tam, L Adler, A Ilstad-Minnihan, C Macaubas… - PloS one, 2017 - journals.plos.org
Monocytes play a critical role in the innate and adaptive immune systems, performing
phagocytosis, presenting antigen, and producing cytokines. They are a heterogeneous …

Zika virus spreads through infection of lymph node-resident macrophages

GV Reynoso, DN Gordon, A Kalia, CC Aguilar… - Cell reports, 2023 - cell.com
To disseminate through the body, Zika virus (ZIKV) is thought to exploit the mobility of
myeloid cells, in particular monocytes and dendritic cells. However, the timing and …

Dysregulated signalling pathways in innate immune cells with cystic fibrosis mutations

S Lara-Reyna, J Holbrook, HH Jarosz-Griffiths… - Cellular and Molecular …, 2020 - Springer
Cystic fibrosis (CF) is one of the most common life-limiting recessive genetic disorders in
Caucasians, caused by mutations in the cystic fibrosis transmembrane conductance …

The interaction between intratumoral microbiome and immunity is related to the prognosis of ovarian cancer

D Sheng, K Yue, H Li, L Zhao, G Zhao, C **… - Microbiology …, 2023 - Am Soc Microbiol
Microbiota can influence the occurrence, development, and therapeutic response of a wide
variety of cancer types by modulating immune responses to tumors. Recent studies have …

Mechanisms of Porphyromonas gingivalis to translocate over the oral mucosa and other tissue barriers

CA de Jongh, TJ de Vries, FJ Bikker… - Journal of Oral …, 2023 - Taylor & Francis
ABSTRACT Introduction The oral pathogen Porphyromonas gingivalis is not only associated
with periodontitis but also with systemic diseases elsewhere in the body. The mechanisms …

[HTML][HTML] Cancer stem cells and macrophages: Molecular connections and future perspectives against cancer

B Aramini, V Masciale, G Grisendi, F Banchelli… - Oncotarget, 2021 - ncbi.nlm.nih.gov
Cancer stem cells (CSCs) have been considered the key drivers of cancer initiation and
progression due to their unlimited self-renewal capacity and their ability to induce tumor …

The role of monocytosis and neutrophilia in atherosclerosis

DA Chistiakov, AV Grechko… - Journal of cellular …, 2018 - Wiley Online Library
Monocytosis and neutrophilia are frequent events in atherosclerosis. These phenomena
arise from the increased proliferation of hematopoietic stem and multipotential progenitor …