Gout is the most common inflammatory arthritis and occurs when hyperuricaemia, sustained
elevation of serum urate levels resulting in supersaturation of body tissues with urate, leads …

Objective To review the epidemiology of gout and associated comorbidities. Methods We
review the key published studies of the epidemiology of gout and associated comorbidities …

Objective To estimate the current prevalence rates and decadal trends of gout and
hyperuricemia in the US, as well as the prevalence of urate‐lowering therapy (ULT) among …

Objectives The burden of gout has been increasing globally. However, little is known about
the global, regional and national distribution and time trend of this disease. We present a …

Importance Gout disparities among Black individuals in the US have recently been
explained by socioclinical factors; however, no information is available among Asian …

Objective To use data from the Global Burden of Disease (GBD) Study 2019 to report the
global, regional and national rates and trends of annual incidence, point prevalence and …

Hyperuricemia is not only a risk factor for gout but also an independent determinant of
hypertension, diabetes, and chronic kidney diseases. Although the incidence of gout in …

Humans do not produce uricase, an enzyme responsible for degrading uric acid. However,
some bacteria residing in the gut can degrade one-third of the dietary and endogenous uric …

Recent evidence suggests that hyperuricemia is an important condition in children and
adolescents, particularly in association with noncommunicable diseases. This review aims …

Gout is a form of prevalent and painful inflammatory arthritis characterized by elevated
serum urate (SUA) levels. The gut microbiota (GM) is believed to influence the development …