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Obesity II: establishing causal links between chemical exposures and obesity
Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …
prevailing view is that obesity results from an imbalance between energy intake and …
[HTML][HTML] The potential roles of post-translational modifications of PPARγ in treating diabetes
X Ji, W Zhang, L Yin, Z Shi, J Luan, L Chen, L Liu - Biomolecules, 2022 - mdpi.com
The number of patients with type 2 diabetes mellitus (T2DM), which is mainly characterized
by insulin resistance and insulin secretion deficiency, has been soaring in recent years …
by insulin resistance and insulin secretion deficiency, has been soaring in recent years …
Adipogenic activity of chemicals used in plastic consumer products
J Völker, F Ashcroft, Å Vedøy… - … science & technology, 2022 - ACS Publications
Bisphenols and phthalates, chemicals frequently used in plastic products, promote obesity in
cell and animal models. However, these well-known metabolism-disrupting chemicals …
cell and animal models. However, these well-known metabolism-disrupting chemicals …
Triphenyl phosphate disturbs the lipidome and induces endoplasmic reticulum stress and apoptosis in JEG-3 cells
Y Wang, J Hong, M Shi, L Guo, L Liu, H Tang, X Liu - Chemosphere, 2021 - Elsevier
Triphenyl phosphate (TPP) is a frequently used aryl organophosphate flame retardant.
Epidemiological studies have shown that TPP and its metabolite diphenyl phosphate (DPP) …
Epidemiological studies have shown that TPP and its metabolite diphenyl phosphate (DPP) …
[HTML][HTML] Lipid metabolic disturbance induced by triphenyl phosphate and hydroxy metabolite in HepG2 cells
J An, J Jiang, W Tang, Y Zhong, G Ren… - Ecotoxicology and …, 2023 - Elsevier
Triphenyl phosphate (TPHP) has been widely used as flame retardants and been detected
with increasing frequency in environment. TPHP can transform into mono-hydroxylated …
with increasing frequency in environment. TPHP can transform into mono-hydroxylated …
White-to-beige and back: Adipocyte conversion and transcriptional reprogramming
Obesity has become a pandemic, as currently more than half a billion people worldwide are
obese. The etiology of obesity is multifactorial, and combines a contribution of hereditary …
obese. The etiology of obesity is multifactorial, and combines a contribution of hereditary …
Proteomic and phosphoproteomic profiling in heart failure with preserved ejection fraction (HFpEF)
Although the prevalence of heart failure with preserved ejection fraction (HFpEF) is
increasing, evidence-based therapies for HFpEF remain limited, likely due to an incomplete …
increasing, evidence-based therapies for HFpEF remain limited, likely due to an incomplete …
Adipogenic Effects of Cresyl Diphenyl Phosphate (Triphenyl Phosphate Alternative) through Peroxisome Proliferator-Activated Receptor Gamma Pathway: A …
L Sun, X Liu, J Du, H Yang, Y Lin, D Yu… - Environmental …, 2024 - ACS Publications
Cresyl diphenyl phosphate (CDP), a novel organophosphate ester (OPE), has been
detected in various environmental and human samples. However, there is very limited …
detected in various environmental and human samples. However, there is very limited …
Remodeling on adipocytic physiology of organophosphorus esters in mature adipocytes
Y Liu, Y Le, M Xu, W Wang, H Chen, Q Zhang… - Environmental …, 2022 - Elsevier
The emerging endocrine disruption chemicals organophosphate esters (OPEs) pose high
risk of metabolic disruption. However, limited information is available on physiological …
risk of metabolic disruption. However, limited information is available on physiological …
Triphenyl phosphate interferes with the synthesis of steroid hormones through the PPARγ/CD36 pathway in human trophoblast JEG‐3 cells
Y Chen, Q Liu, Y Wang, M Jiang, J Zhang… - Environmental …, 2024 - Wiley Online Library
Triphenyl phosphate (TPhP), a chemical commonly found in human placenta and breast
milk, has been shown to disturb the endocrine system. Our previous study confirmed that …
milk, has been shown to disturb the endocrine system. Our previous study confirmed that …