Breast cancer is one of the frequent tumors that seriously endanger the physical and mental
well-being in women. F-box and WD repeat domain-containing 7 (FBXW7) is a neoplastic …

Renal cell carcinoma (RCC) is a prevalent malignancy within the genitourinary system. At
present, patients with high-grade or advanced RCC continue to have a bleak prognosis …

SREBP1 is a transcription factor that influences lipogenesis by regulating key genes
associated with lipid biosynthesis, while AMPK, modulates lipid metabolism by regulating …

Breast cancer (BC) incidence and associated mortality have increased in tandem with the
growth in obesity among the females worldwide. An adipokine, visfatin, has been shown to …

Berardinelli–Seip congenital lipodystrophy type 2 (CGL2) is a very rare human genetic
disorder with potential significance to the understanding of the pathobiology of aging. CGL2 …

The sterol regulatory-element binding proteins (SREBPs) are transcription factors controlling
cholesterol and fatty acid synthesis and metabolism. There are three SREBP proteins …

Methionine (Met) can promote milk fat synthesis in bovine mammary epithelial cells
(BMECs), but the potential molecular mechanism is largely unknown. In this report, we aim …

Palmitic acid (PA) can stimulate milk fat synthesis in mammary gland, but the specific
mechanism is still unclear. In our research, we aim to explore the role and corresponding …

Simple Summary Taxol is a chemotherapy drug used in treatment of multiple cancers. Taxol
works by blocking an essential process of cell division called mitosis. Although, Taxol …

BACKGROUND: Pancreatic ductal adenocarcinoma (PDA) is one of the major human health
challenges with minimal therapeutic benefits due to its late detection, and de novo–and …