Population genomics and local adaptation in wild isolates of a model microbial eukaryote
Elucidating the connection between genotype, phenotype, and adaptation in wild
populations is fundamental to the study of evolutionary biology, yet it remains an elusive …
populations is fundamental to the study of evolutionary biology, yet it remains an elusive …
Revisiting Mortimer's genome renewal hypothesis: heterozygosity, homothallism, and the potential for adaptation in yeast
PM Magwene - Ecological Genomics: Ecology and the Evolution of …, 2014 - Springer
In diploid organisms, the frequency and nature of sexual cycles have a major impact on
genome-wide patterns of heterozygosity. Recent population genomic surveys in the budding …
genome-wide patterns of heterozygosity. Recent population genomic surveys in the budding …
A Bayesian MCMC approach to assess the complete distribution of fitness effects of new mutations: uncovering the potential for adaptive walks in challenging …
The role of adaptation in the evolutionary process has been contentious for decades. At the
heart of the century-old debate between neutralists and selectionists lies the distribution of …
heart of the century-old debate between neutralists and selectionists lies the distribution of …
Analysis of fungal genomes reveals commonalities of intron gain or loss and functions in intron-poor species
Previous evolutionary reconstructions have concluded that early eukaryotic ancestors
including both the last common ancestor of eukaryotes and of all fungi had intron-rich …
including both the last common ancestor of eukaryotes and of all fungi had intron-rich …
Extensive horizontal transfer and homologous recombination generate highly chimeric mitochondrial genomes in yeast
The frequency of horizontal gene transfer (HGT) in mitochondrial DNA varies substantially.
In plants, HGT is relatively common, whereas in animals it appears to be quite rare. It is of …
In plants, HGT is relatively common, whereas in animals it appears to be quite rare. It is of …
Genome-Wide Estimates of Mutation Rates and Spectrum in Schizosaccharomyces pombe Indicate CpG Sites are Highly Mutagenic Despite the Absence of DNA …
We accumulated mutations for 1952 generations in 79 initially identical, haploid lines of the
fission yeast Schizosaccharomyces pombe, and then performed whole-genome sequencing …
fission yeast Schizosaccharomyces pombe, and then performed whole-genome sequencing …
Causes and consequences of genome expansion in fungi
YD Kelkar, H Ochman - Genome Biology and Evolution, 2012 - academic.oup.com
Fungi display a large diversity in genome size and complexity, variation that is often
considered to be adaptive. But because nonadaptive processes can also have important …
considered to be adaptive. But because nonadaptive processes can also have important …
[HTML][HTML] From sequence to function: insights from natural variation in budding yeasts
BACKGROUND: Natural variation offers a powerful approach for assigning function to DNA
sequence—a pressing challenge in the age of high throughput sequencing technologies …
sequence—a pressing challenge in the age of high throughput sequencing technologies …
Transcriptome analysis of the parasite Encephalitozoon cuniculi: an in-depth examination of pre-mRNA splicing in a reduced eukaryote
Abstract Background The microsporidian Encephalitozoon cuniculi possesses one of the
most reduced and compacted eukaryotic genomes. Reduction in this intracellular parasite …
most reduced and compacted eukaryotic genomes. Reduction in this intracellular parasite …
Physicochemical amino acid properties better describe substitution rates in large populations
Substitutions between chemically distant amino acids are known to occur less frequently
than those between more similar amino acids. This knowledge, however, is not reflected in …
than those between more similar amino acids. This knowledge, however, is not reflected in …