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Novel antifungals and treatment approaches to tackle resistance and improve outcomes of invasive fungal disease
Fungal infections are on the rise, driven by a growing population at risk and climate change.
Currently available antifungals include only five classes, and their utility and efficacy in …
Currently available antifungals include only five classes, and their utility and efficacy in …
Antifungal resistance and the role of new therapeutic agents
A Logan, A Wolfe, JC Williamson - Current Infectious Disease Reports, 2022 - Springer
Abstract Purpose of Review Advances in health care over time have led to an evolution in
the epidemiology of invasive fungal infections. There is an increasing concern for antifungal …
the epidemiology of invasive fungal infections. There is an increasing concern for antifungal …
Candida auris: A Quick Review on Identification, Current Treatments, and Challenges
Candida auris is a novel and major fungal pathogen that has triggered several outbreaks in
the last decade. The few drugs available to treat fungal diseases, the fact that this yeast has …
the last decade. The few drugs available to treat fungal diseases, the fact that this yeast has …
[HTML][HTML] What Do We Know about Candida auris? State of the Art, Knowledge Gaps, and Future Directions
Candida auris has unprecedently emerged as a multidrug resistant fungal pathogen,
considered a serious global threat due to its potential to cause nosocomial outbreaks and …
considered a serious global threat due to its potential to cause nosocomial outbreaks and …
Emerging and future strategies in the management of recalcitrant Candida auris
Candida auris is an emerging, multi drug resistant fungal pathogen that has caused
infectious outbreaks in over 45 countries since its first isolation over a decade ago, leading …
infectious outbreaks in over 45 countries since its first isolation over a decade ago, leading …
Novel antifungal agents in clinical trials
Invasive fungal diseases due to resistant yeasts and molds are an important and increasing
public health threat, likely due to a growing population of immunosuppressed hosts …
public health threat, likely due to a growing population of immunosuppressed hosts …
The antifungal pipeline for invasive fungal diseases: what does the future hold?
CF Neoh, W Jeong, DCM Kong… - Expert review of anti …, 2023 - Taylor & Francis
Introduction Over the last two decades, we have experienced pressing needs for new
additions to the antifungal armamentarium given the emergence of resistant fungi, the …
additions to the antifungal armamentarium given the emergence of resistant fungi, the …
Impact of FKS1 Genotype on Echinocandin In Vitro Susceptibility in Candida auris and In Vivo Response in a Murine Model of Infection
Echinocandins are frontline antifungal agents in the management of invasive infections due
to multidrug resistant Candida auris. The study aimed to evaluate echinocandin resistance …
to multidrug resistant Candida auris. The study aimed to evaluate echinocandin resistance …
Promising Drug Candidates and New Strategies for Fighting against the Emerging Superbug Candida auris
Invasive fungal infections represent an expanding threat to public health. During the past
decade, a paradigm shift of candidiasis from Candida albicans to non-albicans Candida …
decade, a paradigm shift of candidiasis from Candida albicans to non-albicans Candida …
Azole resistance in Candida auris: mechanisms and combinatorial therapy
Multidrug resistance Candida auris is a dangerous fungal pathogen that is emerging at an
alarming rate and posing serious threats to public health. C. auris is associated with …
alarming rate and posing serious threats to public health. C. auris is associated with …