The spread of antibiotic resistance represents a global threat to public health, and has been
traditionally attributed to extensive antibiotic uses in clinical and agricultural applications. As …

Borrelia burgdorferi, the spirochetal agent of Lyme disease, is a zoonotic pathogen that is
maintained in a natural cycle that typically involves mammalian reservoir hosts and a tick …

In flowers with dry stigmas, pollen development, pollination, and pollen tube growth require
spatial and temporal regulation of water and nutrient transport. To better understand the …

Xenopus oocytes expressing human aquaporin-7 (AQP7) exhibit greater osmotic water
permeability and 3H-glycerol uptake vs. those expressing the bacterial glycerol facilitator …

For its fundamental relevance, transport of water and glycerol across the erythrocyte
membrane has long been investigated before and after the discovery of aquaporins (AQPs) …

Computing protein–protein association affinities is one of the fundamental challenges in
computational biophysics/biochemistry. The overwhelming amount of statistics in the phase …

Measuring or computing the single-channel permeability of aquaporins/aquaglyceroporins
(AQPs) has long been a challenge. The measured values scatter over an order of magnitude …

MhOR5, an insect olfactory receptor (OR), has an occluded binding site for the odorant
eugenol in both the open and closed states of the ion channel. We used atomistic molecular …

Computing the free energy of binding a ligand to a protein is a difficult task of essential
importance for which purpose various theoretical/computational approaches have been …

AQP7 is one of the four human aquaglyceroporins that facilitate glycerol transport across the
cell membrane, a biophysical process that is essential in human physiology. Therefore, it is …