TSH receptor (TSHR) germline mutations occur as activating mutations in familial non-
autoimmune hyperthyroidism (FNAH) or sporadic non-autoimmune hyperthyroidism (SNAH) …

Three syndromes affecting the thyroid gland are described in the literature separately:
familial nonautoimmune hyperthyroidism, sporadic congenital nonautoimmune …

All cases of familial thyrotoxicosis with absence of evidence of autoimmunity and all children
with persistent isolated neonatal hyperthyroidism should be evaluated for familial non …

Hyperthyroidism is a clinical state that results from high thyroid hormone levels which has
multiple etiologies, manifestations, and potential therapies. Excluding the autoimmune …

Publisher Summary In the practice of medicine, it has long been recognized that endocrine
disorders were caused by too much or too little hormone. However, the etiology of the …

Seven-transmembrane receptors (7TMRs) mediate the majority of physiological responses
to hormones and neurotransmitters in higher organisms. Tertiary structure stability and …

Background: Germline thyrotropin receptor (TSHR) mutations are associated with sporadic
congenital nonautoimmune hyperthyroidism and familial nonautoimmune hyperthyroidism …

Objective To describe clinical and genetic features of a Thai family with non‐autoimmune
hyperthyroidism (NAH) caused by an activating germline mutation in the thyrotropin receptor …

Context: Dominant activating mutations of the TSH receptor are the cause of familial
nonautoimmune hyperthyroidism (FNAH)(inherited mutations affecting the whole gland …

Background: Germline activating mutations of the thyrotropin receptor (TSHR) gene have
been considered as the only known cause of sporadic nonautoimmune hyperthyroidism in …