Head and neck squamous cell carcinomas (HNSCCs) arise in the mucosal lining of the
upper aerodigestive tract. Tobacco and alcohol use have been reported to be associated …

Cellular senescence is a state of stable cell-cycle arrest with secretory features in response
to cellular stress. Historically, it has been considered as an endogenous evolutionary …

The cyclin D-cyclin dependent kinase (CDK) 4/6-inhibitor of CDK4 (INK4)-retinoblastoma
(Rb) pathway controls cell cycle progression by regulating the G1-S checkpoint …

Background Oropharyngeal squamous-cell carcinomas caused by human papillomavirus
(HPV) are associated with favorable survival, but the independent prognostic significance of …

Head and neck squamous cell carcinomas (HNSCCs) are caused by tobacco and alcohol
consumption and by infection with high-risk types of human papillomavirus (HPV). Tumours …

Increased levels of DNA fragments have frequently been found in the blood plasma of
cancer patients. Published data suggest that only a fraction of the DNA in blood plasma is …

Background: High-risk human papillomaviruses (HPVs) are etiologic agents for anogenital
tract cancers and have been detected in head and neck squamous cell carcinomas …

Cyclin-dependent kinases (CDK) 4/6 inhibitors, namely abemaciclib, palbociclib, and
ribociclib, interfere with cell cycle progression, induce cell senescence and might promote …

Head and neck cancers account for less than 5% of all cancers and for less than 3% of all
cancer deaths in the United States. The populations at risk for head and neck cancers are …

Head and neck cancers include neoplasms of the oral cavity, pharynx, and larynx. The risk
of these cancers is strongly associated with smoking and alcohol ingestion. There have …