Marine natural products

AR Carroll, BR Copp, RA Davis, RA Keyzers… - Natural Product …, 2020 - pubs.rsc.org
This review covers the literature published between January and December in 2018 for
marine natural products (MNPs), with 717 citations (706 for the period January to December …

Cyclic peptides in pipeline: what future for these great molecules?

L Costa, E Sousa, C Fernandes - Pharmaceuticals, 2023 - mdpi.com
Cyclic peptides are molecules that are already used as drugs in therapies approved for
various pharmacological activities, for example, as antibiotics, antifungals, anticancer, and …

[HTML][HTML] Recent Advances in Marine-Derived Compounds as Potent Antibacterial and Antifungal Agents: A Comprehensive Review

D Bharathi, J Lee - Marine Drugs, 2024 - mdpi.com
The increase in antimicrobial resistance (AMR) in microorganisms is a significant global
health concern. Various factors contribute to AMR, including alterations in cell membrane …

[HTML][HTML] Therapeutic Potential of Marine-Derived Cyclic Peptides as Antiparasitic Agents

R Ribeiro, L Costa, E Pinto, E Sousa, C Fernandes - Marine Drugs, 2023 - mdpi.com
Parasitic diseases still compromise human health. Some of the currently available
therapeutic drugs have limitations considering their adverse effects, questionable efficacy …

Unlocking marine microbial treasures: new PBP2a-targeted antibiotics elicited by metals and enhanced by RSM-driven transcriptomics and chemoinformatics

SS Hassan, JJ Wu, T Li, X Ye, A Rehman, S Yan… - Microbial Cell …, 2024 - Springer
Elicitation through abiotic stress, including heavy metals, is a new natural product drug
discovery technique. In this research, three compounds 1, 2, and 6, were achieved by …

Metabolomics of natural samples: A tutorial review on the latest technologies

AB Eshawu, VV Ghalsasi - Journal of Separation Science, 2024 - Wiley Online Library
Metabolomics is the study of metabolites present in a living system. It is a rapidly growing
field aimed at discovering novel compounds, studying biological processes, diagnosing …

[HTML][HTML] A Novel Bacitracin-like Peptide from Mangrove-Isolated Bacillus paralicheniformis NNS4-3 against MRSA and Its Genomic Insights

N Sermkaew, A Atipairin, T Wanganuttara, S Krobthong… - Antibiotics, 2024 - mdpi.com
The global rise of antimicrobial resistance (AMR) presents a critical challenge necessitating
the discovery of novel antimicrobial agents. Mangrove microbes are valuable sources of …

[HTML][HTML] The Marine Bacterial Genus Euzebya Is Distributed Worldwide in Terrestrial Environments: A Review

JL Gonzalez-Pimentel, T Martin-Pozas, V Jurado… - Applied Sciences, 2023 - mdpi.com
The advent of molecular tools, and particularly next-generation sequencing, has
dramatically changed our knowledge of the diversity of microbial life on Earth. In recent …

Dissolved Carbon Dioxide: The Lifespan of Staphylococcus aureus and Enterococcus faecalis in Bottled Carbonated Mineral Water

M Schalli, S Platzer, R Schmutz, P Ofner-Kopeinig… - Biology, 2023 - mdpi.com
Simple Summary The consumption of bottled mineral water has been rising in the last
decades. During the water bottling process, the risk of bacterial contamination with pathogen …

Antiproliferative metabolites against glioma cells from the marine-associated actinomycete Streptomyces sp. ZZ735

Q Dai, M Ma, N Wang, Y Zhou, Z Zhang - Fitoterapia, 2024 - Elsevier
Metabolites produced by the genus Streptomyces are the most important resource for
discovering bioactive compounds. In this study, chemical investigation on the metabolites …