Recent Approaches for the Topical Treatment of Psoriasis Using Nanoparticles

K Bodnár, P Fehér, Z Ujhelyi, I Bácskay, L Józsa - Pharmaceutics, 2024 - mdpi.com
Psoriasis (PSO) is a chronic autoimmune skin condition characterized by the rapid and
excessive growth of skin cells, which leads to the formation of thick, red, and scaly patches …

Novel antiarthritic mechanisms of azelaic acid against CFA-induced arthritis in rats by modulating pro-and anti-inflammatory cytokines network

NT Sial, A Malik, U Iqbal, MH Mehmood… - …, 2024 - Springer
An immunologic system attacking the body's own tissues is a hallmark of autoimmune
disorders, which encompass a wide range of unique conditions. Numerous essential …

Development and Evaluation of Dutasteride Nanoemulgel for the Topical Delivery against Androgenic Alopecia

M Alam, A Mishra, KS Yadav, D Pradhan… - Pharmaceutical …, 2024 - benthamdirect.com
Background: Dutasteride is approximately three times more potent than finasteride in
treating alopecia. For reducing systemic exposure to dihydrotestosterone (DHT) …

Microsponge-Based Gel Loaded with Immunosuppressant as a Simple and Valuable Strategy for Psoriasis Therapy: Determination of Pro-Inflammatory Response …

Y Mehmood, H Shahid, UI ul Huq, H Rafeeq… - Gels, 2023 - mdpi.com
Tacrolimus (TL) is a topical calcineurin inhibitor immunosuppressive drug widely used to
manage various skin disorders. Herein, we report a TL-loaded microsphere gel formulation …

Physicochemical Stimuli-Mediated Precipitation Approach for the Modulation of Rifampicin's Dissolution and Oral Bioavailability

VK Rai, D Pradhan, J Halder, TK Rajwar, R Mahanty… - AAPS …, 2024 - Springer
The intricate process of protein binding orchestrates crucial drug interactions within the
bloodstream, facilitating the formation of soluble complexes. This research endeavours to …

Spray-Dried Mucoadhesive Re-dispersible Gargle of Chlorhexidine for Improved Response Against Throat Infection: Formulation Development, In Vitro and In Vivo …

VK Rai, A Kumar, D Pradhan, J Halder, TK Rajwar… - AAPS …, 2024 - Springer
Drug delivery to the buccal mucosa is one of the most convenient ways to treat common
mouth problems. Here, we propose a spray-dried re-dispersible mucoadhesive controlled …

Exploring the Therapeutic Potential: MTX/TAC Nanoformulation in IMQ-Induced Psoriasis Models

MI Asad, D Khan, AU Rehman, N Ahmed, A Elaissari - Chemistry Africa, 2024 - Springer
Psoriasis, an autoimmune disorder affecting 2–3% population of the world and it does not
rely sufficiently on the monotherapy, which suggests combinatory approaches for …

Development of Nanoemulsion-Based Gel of Betulin for the Treatment of Psoriasis-Like Skin Inflammation in a Small Animal Model

D Prakash, A Chaudhary - Pharmaceutical Nanotechnology, 2024 - benthamdirect.com
Introduction/Background This study aimed to introduce a gel (NEG) formulation containing
betulin-loaded nanoemulsions for topical psoriasis treatment. Materials and Methods The …