Methicillin-resistant Staphylococcus aureus: molecular characterization, evolution, and epidemiology

S Lakhundi, K Zhang - Clinical microbiology reviews, 2018 - Am Soc Microbiol
Staphylococcus aureus, a major human pathogen, has a collection of virulence factors and
the ability to acquire resistance to most antibiotics. This ability is further augmented by …

How antimicrobial resistance is linked to climate change: an overview of two intertwined global challenges

R Magnano San Lio, G Favara, A Maugeri… - International journal of …, 2023 - mdpi.com
Globally, antimicrobial resistance (AMR) and climate change (CC) are two of the top health
emergencies, and can be considered as two interlinked public health priorities. The complex …

Antibiotic resistance—the need for global solutions

R Laxminarayan, A Duse, C Wattal… - The Lancet infectious …, 2013 - thelancet.com
The causes of antibiotic resistance are complex and include human behaviour at many
levels of society; the consequences affect everybody in the world. Similarities with climate …

Emergence of methicillin resistance predates the clinical use of antibiotics

J Larsen, CL Raisen, X Ba, NJ Sadgrove… - Nature, 2022 - nature.com
The discovery of antibiotics more than 80 years ago has led to considerable improvements
in human and animal health. Although antibiotic resistance in environmental bacteria is …

[HTML][HTML] Application of next generation sequencing in clinical microbiology and infection prevention

RH Deurenberg, E Bathoorn, MA Chlebowicz… - Journal of …, 2017 - Elsevier
Current molecular diagnostics of human pathogens provide limited information that is often
not sufficient for outbreak and transmission investigation. Next generation sequencing …

Antibiotics in agriculture and the risk to human health: how worried should we be?

Q Chang, W Wang, G Regev‐Yochay… - Evolutionary …, 2015 - Wiley Online Library
The use of antibiotics in agriculture is routinely described as a major contributor to the
clinical problem of resistant disease in human medicine. While a link is plausible, there are …

The emergence of mecC methicillin-resistant Staphylococcus aureus

GK Paterson, EM Harrison, MA Holmes - Trends in microbiology, 2014 - cell.com
The report of methicillin-resistant Staphylococcus aureus (MRSA) encoding a divergent
mecA gene in 2011 was highly significant. This homologue, designated mecC, poses …

Livestock-associated MRSA: the impact on humans

C Cuny, LH Wieler, W Witte - Antibiotics, 2015 - mdpi.com
During the past 25 years an increase in the prevalence of methicillin-resistant
Staphylococcus aureus (HA-MRSA) was recorded worldwide. Additionally, MRSA infections …

Current and emerging Legionella diagnostics for laboratory and outbreak investigations

JW Mercante, JM Winchell - Clinical microbiology reviews, 2015 - Am Soc Microbiol
Legionnaires' disease (LD) is an often severe and potentially fatal form of bacterial
pneumonia caused by an extensive list of Legionella species. These ubiquitous freshwater …

Emergence of epidemic multidrug-resistant Enterococcus faecium from animal and commensal strains

F Lebreton, W van Schaik, A Manson McGuire… - MBio, 2013 - Am Soc Microbiol
Enterococcus faecium, natively a gut commensal organism, emerged as a leading cause of
multidrug-resistant hospital-acquired infection in the 1980s. As the living record of its …