Genetic variation in DNA repair genes can modulate DNA repair capacity and may be
related to cancer risk. However, study findings have been inconsistent. Inheritance of variant …

Breast cancer (BC) is the most common cancer among women worldwide. The aetiology
and carcinogenesis of BC are not clearly defined, although genetic, hormonal, lifestyle and …

Cell cycle checkpoint kinase 2 (CHEK2) is a checkpoint kinase that plays an important role
in the DNA damage signaling network. Numerous epidemiological studies have evaluated …

Background Vitamin D status may influence the risk of Insulin resistance related diseases
such as Type 2 diabetes (T2DM), metabolic syndrome (MetS), and polycystic ovarian …

Background MicroRNAs expression has been extensively studied in hepatocellular
carcinoma but little is known regarding the relationship, if any, with inflammation, production …

Background Despite conflicting results, considerable evidence suggests the association
between single nucleotide polymorphisms in MTHFR, XRCC1 and OGG1 genes and, risk of …

Background Alterations in the redox balance are involved in the origin, promotion and
progression of cancer. Inter-individual differences in the oxidative stress regulation can …

The role of the DNA repair genes OGG1, XRCC1, XRCC2 and XRCC3 on differentiated
thyroid cancer (DTC) susceptibility was examined in 881 individuals (402 DTC and 479 …

Altered DNA repair capacity can result in increased susceptibility to cancer. The base
excision repair (BER) pathway effectively removes DNA damage caused by ionizing …

Although genetic susceptibility to nasopharyngeal carcinoma (NPC) has been recognized
for a long time, little is known about the responsible genes. X‐Ray repair cross …