Snake venoms are mixtures of toxins that vary extensively between and within snake
species. This variability has serious consequences for the management of the world's 1.8 …

Animal venoms have evolved over millions of years for prey capture and defense from
predators and rivals. Snake venoms, in particular, have evolved a wide diversity of peptides …

There is increasing recognition of the public health importance of snakebite envenoming.
Worldwide annual incidence is likely to be 5 million bites, with mortality exceeding 150 000 …

Snakebite is a medical emergency causing high mortality and morbidity in rural tropical
communities that typically experience delayed access to unaffordable therapeutics. Viperid …

Snake venoms are heterogeneous mixtures of proteins and peptides used for prey
subjugation. With modern proteomics there has been a rapid expansion in our knowledge of …

Wnt dependency and Lgr5 expression define multiple mammalian epithelial stem cell types.
Under defined growth factor conditions, such adult stem cells (ASCs) grow as 3D organoids …

Many issues and complications in treating snakebite are a result of poor human social,
economic and clinical intervention and management. As such, there is scope for significant …

In this study, we present high-throughput (HT) venomics, a novel analytical strategy capable
of performing a full proteomic analysis of a snake venom within 3 days. This methodology …

Background The World Health Organization's strategy to halve snakebite mortality and
morbidity by 2030 includes an emphasis on a risk-benefit process assessing the preclinical …

Snakebite envenoming causes 138,000 deaths annually, and~ 400,000 victims are left with
permanent disabilities. Envenoming by saw-scaled vipers (Viperidae: Echis) leads to …