Cytogenetics of Bone and Soft Tissue Tumors [1]. In view of the remarkable developments in
this field since 1994, both in the cytogenetic and particularly in the molecular genetic …

Members of the FET protein family, consisting of FUS, EWSR1, and TAF15, bind to RNA and
contribute to the control of transcription, RNA processing, and the cytoplasmic fates of …

Sarcomas comprise a heterogeneous group of mesenchymal neoplasms. They can be
grouped into 2 general categories, soft tissue sarcoma and primary bone sarcoma, which …

Translocated in liposarcoma, Ewing's sarcoma and TATA-binding protein-associated factor
15 constitute an interesting and important family of proteins known as the TET proteins. The …

Results The mouse TLS gene was disrupted in embryonic stem (ES) cells. The TLS coding
region was interrupted inside exon 8 (immediately upstream of the RNA recognition motif) by …

CHOP/gadd153 is a transcription factor induced by cellular stresses such as UV light,
genotoxic agents, and protein misfolding in the endoplasmic reticulum. The fact that these …

Lubricin is a secreted, cytoprotective glycoprotein that contributes to the essential boundary
lubrication mechanisms necessary for maintaining low friction levels at articular cartilage …

Lubrication of cartilage involves a variety of physical and chemical factors, including lubricin,
a synovial glycoprotein that has been shown to be a boundary lubricant. It is unclear how …

Lubricin, also commonly referred to as superficial zone protein (SZP) and proteoglycan 4
(PRG4), is a multifaceted, cytoprotective glycoprotein that contributes to the boundary …

Lipoblastomas are rare soft tissue tumors that occur primarily in young children. They
typically contain variably differentiated adipocytes, primitive mesenchymal cells, myxoid …