In 1982, investigation of two outbreaks of a distinctive bloody diarrheal syndrome led to the
identification of a new bacterial pathogen, Escherichia coli O157: H7 (1). In the decade …

Over the years, approaches to the epidemiological analysis of infectious disease have
undergone a remarkable evolutionary transition moving from phenotypic to molecular in …

Intact yeast cells treated with alkali cations took up plasmid DNA. Li+, Cs+, Rb+, K+, and
Na+ were effective in inducing competence. Conditions for the transformation of …

Procedures are described for the detection and isolation of plasmids of various sizes (2.6 to
350 megadaltons) that are harbored in species of Agrobacterium, Rhizobium, Escherichia …

We demonstrate that in liquid cultures, defined in this study as a mass habitat, the outcome
of competition between Escherichia coli that produce an antibacterial toxin (colicin) and …

Objective.—Esherichia coliO157: H7 causes hemorrhagic colitis and the hemolytic uremic
syndrome. In the fall of 1991, an outbreak ofE coliO157: H7 infections in southeastern …

Two outbreaks of hemorrhagic colitis, a newly recognized syndrome characterized by
bloody diarrhea, severe abdominal pain, and little or no fever, occurred in 1982. No …

Study Objective: To describe the spectrum of illnesses associated with Escherichia coli
0157: H7 infections. Design: Described an outbreak that showed the broad spectrum of …

We examined 1,266 fecal specimens from healthy cattle during the investigations of two
sporadic cases of hemolytic uremic syndrome associated with raw milk consumption and an …

Nosocomial infections are an important source of morbidity and mortality in hospital settings,
afflicting an estimated 2 million patients in United States each year. This number represents …