Prostate cancer (PCa) accounts for a high number of deaths in males with no available
curative treatments. Patients with PCa are commonly diagnosed in advanced stages due to …

Gastrointestinal (GI) cancers with a high incidence rate and adverse complications are
related to severe morbidity and mortality around the world. MicroRNAs (miRs) are potential …

Immune response, proliferation, migration and angiogenesis are juts a few of cellular events
that are regulated by transforming growth factor-β (TGF-β) in cells. A number of studies have …

Bladder cancer accounts for high morbidity and mortality around the world and its incidence
rate is suggested to be higher in following years. A number of factors involve in bladder …

Macrophages are immune cells that play different roles under different physiological
conditions. They are present in all tissues where they primarily protect from bacteria and …

MicroRNAs (miRNAs) play a critical role in regulation of numerous biological processes and
pathogenesis of a variety of diseases. In addition, miRNAs contribute to carcinogenesis by …

Colorectal cancer is one of the most common cancers among the elderly, which is also seen
in the forms of hereditary syndromes occurring in younger individuals. Numerous studies …

Background Acute myeloid leukemia (AML) is a hematopoietic malignancy with poor
outcomes, especially in older AML patients. Tumor necrosis factor-related apoptosis …

Cerebral ischemia/reperfusion injury has emerged as an intricate mechanism. However,
identification of wide-ranging mechanisms which mechanistically regulate reperfusion …

The DNA methyltransferase (DNMT) family constitutes a conserved set of DNA-modifying
enzymes which have essential functions in the modulation of epigenetics. The fundamental …