Mechanisms of BCL-2 family proteins in mitochondrial apoptosis

PE Czabotar, AJ Garcia-Saez - Nature reviews Molecular cell biology, 2023 - nature.com
The proteins of the BCL-2 family are key regulators of mitochondrial apoptosis, acting as
either promoters or inhibitors of cell death. The functional interplay and balance between the …

Mitochondria in health, disease, and aging

JS Harrington, SW Ryter, M Plataki… - Physiological …, 2023 - journals.physiology.org
Mitochondria are well known as organelles responsible for the maintenance of cellular
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …

Oxygen‐Vacancy‐Rich Piezoelectric BiO2−x Nanosheets for Augmented Piezocatalytic, Sonothermal, and Enzymatic Therapies

L Yang, B Tian, Y **e, S Dong, M Yang… - Advanced …, 2023 - Wiley Online Library
Piezocatalytic therapy is a new‐emerging reactive oxygen species (ROS)‐enabled
therapeutic strategy that relies on built‐in electric field and energy‐band bending of …

The double-edged roles of ROS in cancer prevention and therapy

Y Wang, H Qi, Y Liu, C Duan, X Liu, T **a… - …, 2021 - pmc.ncbi.nlm.nih.gov
Reactive oxygen species (ROS) serve as cell signaling molecules generated in oxidative
metabolism and are associated with a number of human diseases. The reprogramming of …

ROS in cancer therapy: the bright side of the moon

B Perillo, M Di Donato, A Pezone, E Di Zazzo… - … & molecular medicine, 2020 - nature.com
Reactive oxygen species (ROS) constitute a group of highly reactive molecules that have
evolved as regulators of important signaling pathways. It is now well accepted that moderate …

Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease

Z Chen, R Tian, Z She, J Cai, H Li - Free Radical Biology and Medicine, 2020 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver
disease worldwide and is strongly associated with the presence of oxidative stress …

Bimetallic Organic Frameworks of High Piezovoltage for Sono‐Piezo Dynamic Therapy

Q Wang, Y Tian, M Yao, J Fu, L Wang… - Advanced …, 2023 - Wiley Online Library
Piezoelectric materials produce charges to directly act on cancer medium or promote the
generation of reactive oxygen species (ROS) for novel tumor therapy triggered by …

[HTML][HTML] β-Sitosterol as a promising anticancer agent for chemoprevention and chemotherapy: mechanisms of action and future prospects

H Wang, Z Wang, Z Zhang, J Liu, L Hong - Advances in Nutrition, 2023 - Elsevier
Cancer is one of the primary causes of death worldwide, and its incidence continues to
increase yearly. Despite significant advances in research, the search for effective and …

Mitochondrial event as an ultimate step in ferroptosis

SJ Oh, M Ikeda, T Ide, KY Hur, MS Lee - Cell death discovery, 2022 - nature.com
In ferroptosis, the roles of mitochondria have been controversial. To explore the role of
mitochondrial events in ferroptosis, we employed mitochondrial DNA-depleted ρ0 cells that …

Platelet membrane‐camouflaged magnetic nanoparticles for ferroptosis‐enhanced cancer immunotherapy

Q Jiang, K Wang, X Zhang, B Ouyang, H Liu, Z Pang… - Small, 2020 - Wiley Online Library
Although cancer immunotherapy has emerged as a tremendously promising cancer therapy
method, it remains effective only for several cancers. Photoimmunotherapy (eg …