Microbial biofilm: formation, architecture, antibiotic resistance, and control strategies

MA Rather, K Gupta, M Mandal - Brazilian Journal of Microbiology, 2021 - Springer
The assembly of microorganisms over a surface and their ability to develop resistance
against available antibiotics are major concerns of interest. To survive against harsh …

Biofilms as promoters of bacterial antibiotic resistance and tolerance

C Uruén, G Chopo-Escuin, J Tommassen… - Antibiotics, 2020 - mdpi.com
Multidrug resistant bacteria are a global threat for human and animal health. However, they
are only part of the problem of antibiotic failure. Another bacterial strategy that contributes to …

Bacteriophage therapy against Pseudomonas aeruginosa biofilms: a review

Z Chegini, A Khoshbayan, M Taati Moghadam… - Annals of clinical …, 2020 - Springer
Abstract Multi-Drug Resistant (MDR) Pseudomonas aeruginosa is one of the most important
bacterial pathogens that causes infection with a high mortality rate due to resistance to …

Phages for phage therapy: isolation, characterization, and host range breadth

P Hyman - Pharmaceuticals, 2019 - mdpi.com
For a bacteriophage to be useful for phage therapy it must be both isolated from the
environment and shown to have certain characteristics beyond just killing strains of the …

[HTML][HTML] Antibiotic resistance in agriculture: Perspectives on upcoming strategies to overcome upsurge in resistance

A Mann, K Nehra, JS Rana, T Dahiya - Current research in microbial …, 2021 - Elsevier
Antibiotic resistance is a massive problem rising constantly and spreading rapidly since the
past decade. The major underlying mechanism responsible for this problem is an overuse or …

Current challenges and future opportunities of phage therapy

DP Pires, AR Costa, G Pinto, L Meneses… - FEMS microbiology …, 2020 - academic.oup.com
Antibiotic resistance is a major public health challenge worldwide, whose implications for
global health might be devastating if novel antibacterial strategies are not quickly …

Interference in bacterial quorum sensing: a biopharmaceutical perspective

B Rémy, S Mion, L Plener, M Elias… - Frontiers in …, 2018 - frontiersin.org
Numerous bacteria utilize molecular communication systems referred to as quorum sensing
(QS) to synchronize the expression of certain genes regulating, among other aspects, the …

[HTML][HTML] Biofilms: Formation, drug resistance and alternatives to conventional approaches

R Mirghani, T Saba, H Khaliq, J Mitchell, L Do… - AIMS …, 2022 - ncbi.nlm.nih.gov
Biofilms are aggregates of bacteria, in most cases, which are resistant usually to broad-
spectrum antibiotics in their typical concentrations or even in higher doses. A trend of …

Phage-antibiotic synergy is driven by a unique combination of antibacterial mechanism of action and stoichiometry

C Gu Liu, SI Green, L Min, JR Clark, KC Salazar… - MBio, 2020 - Am Soc Microbiol
The continued rise in antibiotic resistance is precipitating a medical crisis. Bacteriophage
(phage) has been hailed as one possible therapeutic option to augment the efficacy of …

Phages for biofilm removal

C Ferriol-González, P Domingo-Calap - Antibiotics, 2020 - mdpi.com
Biofilms are clusters of bacteria that live in association with surfaces. Their main
characteristic is that the bacteria inside the biofilms are attached to other bacterial cells and …