Kidney physiology and susceptibility to acute kidney injury: implications for renoprotection

H Scholz, FJ Boivin, KM Schmidt-Ott… - Nature Reviews …, 2021‏ - nature.com
Kidney damage varies according to the primary insult. Different aetiologies of acute kidney
injury (AKI), including kidney ischaemia, exposure to nephrotoxins, dehydration or sepsis …

Mechanisms of maladaptive repair after AKI leading to accelerated kidney ageing and CKD

DA Ferenbach, JV Bonventre - Nature Reviews Nephrology, 2015‏ - nature.com
Acute kidney injury is an increasingly common complication of hospital admission and is
associated with high levels of morbidity and mortality. A hypotensive, septic, or toxic insult …

[HTML][HTML] The role of renal hypoxia in the pathogenesis of diabetic kidney disease: a promising target for newer renoprotective agents including SGLT2 inhibitors?

AC Hesp, JA Schaub, PV Prasad, V Vallon… - Kidney international, 2020‏ - Elsevier
Diabetic kidney disease is the most common cause of end-stage kidney disease and poses
a major global health problem. Finding new, safe, and effective strategies to halt this disease …

[کتاب][B] International law

MD Evans - 2014‏ - books.google.com
New chapters on" International Human Rights Law" by Sir Nigel Rodley and" International
Investment Law" ny Surya Subedi. Key new materials and cases now covered include: ILC …

Sepsis‐induced acute kidney injury: A disease of the microcirculation

S Ma, RG Evans, N Iguchi, M Tare… - …, 2019‏ - Wiley Online Library
AKI is a common complication of sepsis and is significantly associated with mortality. Sepsis
accounts for more than 50% of the cases of AKI, with a mortality rate of up to 40%. The …

Sepsis-associated acute kidney injury

R Alobaidi, RK Basu, SL Goldstein, SM Bagshaw - Seminars in nephrology, 2015‏ - Elsevier
Acute kidney injury (AKI) is an epidemic problem. Sepsis has long been recognized as a
foremost precipitant of AKI. Sepsis-associated AKI (SA-AKI) portends a high burden of …

[HTML][HTML] Role of perioperative hypotension in postoperative acute kidney injury: a narrative review

YR Lankadeva, CN May, R Bellomo… - British journal of …, 2022‏ - Elsevier
Perioperative hypotension is common and associated with poor outcomes, including acute
kidney injury (AKI). The mechanistic link between perioperative hypotension and AKI is at …

Arterial spin labelling MRI to measure renal perfusion: a systematic review and statement paper

A Odudu, F Nery, AA Harteveld… - Nephrology Dialysis …, 2018‏ - academic.oup.com
Renal perfusion provides the driving pressure for glomerular filtration and delivers the
oxygen and nutrients to fuel solute reabsorption. Renal ischaemia is a major mechanism in …

[HTML][HTML] Intrarenal and urinary oxygenation during norepinephrine resuscitation in ovine septic acute kidney injury

YR Lankadeva, J Kosaka, RG Evans, SR Bailey… - Kidney international, 2016‏ - Elsevier
Norepinephrine is the principal vasopressor used to restore blood pressure in sepsis, but its
effects on intrarenal oxygenation are unknown. To clarify this, we examined renal cortical …

Acute kidney injury and chronic kidney disease: From the laboratory to the clinic

DA Ferenbach, JV Bonventre - Nephrologie & therapeutique, 2016‏ - Elsevier
Chronic kidney disease and acute kidney injury have traditionally been considered as
separate entities with different etiologies. This view has changed in recent years, with …