Immune Evasion Strategies of Trypanosoma brucei within the Mammalian Host: Progression to Pathogenicity
B Stijlemans, G Caljon, J Van Den Abbeele… - Frontiers in …, 2016 - frontiersin.org
The diseases caused by African trypanosomes (AT) are of both medical and veterinary
importance and have adversely influenced the economic development of sub-Saharan …
importance and have adversely influenced the economic development of sub-Saharan …
Induced transient immune tolerance in ticks and vertebrate host: a keystone of tick-borne diseases?
N Boulanger, S Wikel - Frontiers in immunology, 2021 - frontiersin.org
Ticks and tick transmitted infectious agents are increasing global public health threats due to
increasing abundance, expanding geographic ranges of vectors and pathogens, and …
increasing abundance, expanding geographic ranges of vectors and pathogens, and …
Tick saliva and its role in pathogen transmission
PA Nuttall - Wiener klinische Wochenschrift, 2019 - Springer
Tick saliva is a complex mixture of peptidic and non-peptidic molecules that aid
engorgement. The composition of tick saliva changes as feeding progresses and the tick …
engorgement. The composition of tick saliva changes as feeding progresses and the tick …
Discovery of exosomes from tick saliva and salivary glands reveals therapeutic roles for CXCL12 and IL-8 in wound healing at the tick–human skin interface
Ticks secrete various anti-coagulatory, anti-vasoconstrictory, anti-inflammatory, and anti-
platelet aggregation factors in their saliva at the bite site during feeding to evade host …
platelet aggregation factors in their saliva at the bite site during feeding to evade host …
Skin microbiota secretomes modulate cutaneous innate immunity against Borrelia burgdorferi ss
F Baquer, B Jaulhac, C Barthel, M Paz, J Wolfgramm… - Scientific Reports, 2023 - nature.com
In Lyme borreliosis, the skin constitutes a major interface for the host, the bacteria and the
tick. Skin immunity is provided by specialized immune cells but also by the resident cells: the …
tick. Skin immunity is provided by specialized immune cells but also by the resident cells: the …
Neutrophils enhance early Trypanosoma brucei infection onset
G Caljon, D Mabille, B Stijlemans, C De Trez… - Scientific reports, 2018 - nature.com
In this study, Trypanosoma brucei was naturally transmitted to mice through the bites of
infected Glossina morsitans tsetse flies. Neutrophils were recruited rapidly to the bite site …
infected Glossina morsitans tsetse flies. Neutrophils were recruited rapidly to the bite site …
Plasticity in early immune evasion strategies of a bacterial pathogen
Borrelia burgdorferi is one of the few extracellular pathogens capable of establishing
persistent infection in mammals. The mechanisms that sustain long-term survival of this …
persistent infection in mammals. The mechanisms that sustain long-term survival of this …
The tick protein sialostatin L2 binds to annexin A2 and inhibits NLRC4-mediated inflammasome activation
X Wang, DK Shaw, OS Sakhon, GA Snyder… - Infection and …, 2016 - Am Soc Microbiol
Tick saliva contains a number of effector molecules that inhibit host immunity and facilitate
pathogen transmission. How tick proteins regulate immune signaling, however, is …
pathogen transmission. How tick proteins regulate immune signaling, however, is …
Cross-alteration of murine skin and tick microbiome concomitant with pathogen transmission after Ixodes ricinus bite
N Boulanger, JLM Insonere, S Van Blerk, C Barthel… - Microbiome, 2023 - Springer
Background Ticks are major vectors of diseases affecting humans such as Lyme disease or
domestic animals such as anaplasmosis. Cross-alteration of the vertebrate host skin …
domestic animals such as anaplasmosis. Cross-alteration of the vertebrate host skin …
Immune responses to ectoparasites of horses, with a focus on insect bite hypersensitivity
AD Wilson - Parasite immunology, 2014 - Wiley Online Library
Horses are affected by a wide variety of arthropod ectoparasites, ranging from lice which
spend their entire life on the host, through ticks which feed over a period of days, to …
spend their entire life on the host, through ticks which feed over a period of days, to …