Detection of incipient Alzheimer disease (AD) pathophysiology is critical to identify
preclinical individuals and target potentially disease-modifying therapies towards them …

Navigation ability varies widely across humans. Prior studies have reported that being
younger and a male has an advantage for navigation ability. However, these studies have …

The entorhinal cortex is one of the first regions to exhibit neurodegeneration in Alzheimer's
disease, and as such identification of entorhinal cortex dysfunction may aid detection of the …

Spatial navigation is emerging as a critical factor in identifying preclinical Alzheimer's
disease (AD). However, the impact of interindividual navigation ability and demographic risk …

Background: Spatial navigation is the ability to estimate one's position on the basis of
environmental and self-motion cues. Spatial memory is the cognitive substrate underlying …

The hippocampus is regarded as the pivotal structure for episodic memory symptoms
associated with Alzheimer's disease (AD) pathophysiology. However, what is often …

Hippocampal and basal forebrain (BF) atrophy is associated with allocentric navigation
impairment in Alzheimer's disease (AD) and may lead to recruitment of compensatory …

Background: Traditional methods for assessing memory are expensive and have high
administrative costs. Memory assessment is important for establishing cognitive impairment …

Purpose Identification of demographic, physical/physiological, lifestyle and genetic factors
contributing to the onset of dementia, specifically Alzheimer disease (AD), and …

Objective: Spatial disorientation is common in Alzheimer's disease (AD), Mild Cognitive
Impairment (MCI), and preclinical individuals with AD biomarkers. However, traditional …