Simple Summary This review will comprise an overview of insulin and its history, structure,
synthesis, secretion, signaling, and peripheral and brain roles. Further, the impact that …

Alzheimer's disease (AD) is the most widespread form of dementia, characterized by
memory loss and reduction of cognitive functions that strongly interfere with normal daily life …

Aggregation of the amyloid-β (Aβ) peptide is considered a central event in the pathogenesis
of Alzheimer's disease (AD). In order to bypass methodological bias related to a variety of …

A growing body of evidence shows the protective role of insulin in Alzheimer's disease (AD).
A nanogel system (NG) to deliver insulin to the brain, as a tool for the development of a new …

Oxidative stress and dysfunctional mitochondria are among the earliest events in AD,
triggering neurodegeneration. The use of natural antioxidants could be a neuroprotective …

Background Aβ 1-42 peptide abnormal production is associated with the development and
maintenance of neuroinflammation and oxidative stress in brains from Alzheimer disease …

Fibril deposit formation of amyloid β-protein (Aβ) in the brain is a hallmark of Alzheimer's
disease (AD). Increasing evidence suggests that toxicity is linked to diffusible Aβ oligomers …

Several neurodegenerative diseases, including Alzheimer's, Parkinson's, Huntington's and
prion diseases, are characterized pathognomonically by the presence of intra-and/or …

The onset of Alzheimer disease (AD) is influenced by several risk factors comprising
diabetes. Within this context, antidiabetic drugs, including metformin, are investigated for …

Cyanobacteria have been recognized as a source of bioactive molecules to be employed in
nutraceuticals, pharmaceuticals, and functional foods. An extract of Aphanizomenon flos …