[HTML][HTML] Metformin: multi-faceted protection against cancer
S Del Barco, A Vazquez-Martin, S Cufí… - Oncotarget, 2011 - ncbi.nlm.nih.gov
The biguanide metformin, a widely used drug for the treatment of type 2 diabetes, may exert
cancer chemopreventive effects by suppressing the transformative and hyperproliferative …
cancer chemopreventive effects by suppressing the transformative and hyperproliferative …
Current status and application of metformin for prostate cancer: a comprehensive review
HK Ahn, YH Lee, KC Koo - International journal of molecular sciences, 2020 - mdpi.com
Metformin, an oral biguanide used for first-line treatment of type 2 diabetes mellitus, has
attracted attention for its anti-proliferative and anti-cancer effects in several solid tumors …
attracted attention for its anti-proliferative and anti-cancer effects in several solid tumors …
Endocrinology of the aging prostate: current concepts
R Cannarella, RA Condorelli, F Barbagallo… - Frontiers in …, 2021 - frontiersin.org
Benign prostate hyperplasia (BPH), one of the most common diseases in older men,
adversely affects quality-of-life due to the presence of low urinary tract symptoms (LUTS) …
adversely affects quality-of-life due to the presence of low urinary tract symptoms (LUTS) …
Exercise-induced biochemical changes and their potential influence on cancer: a scientific review
Aim To review and discuss the available international literature regarding the indirect and
direct biochemical mechanisms that occur after exercise, which could positively, or …
direct biochemical mechanisms that occur after exercise, which could positively, or …
Metformin and prostate cancer: a new role for an old drug
Abstract Purpose of Review Since epidemiological studies first demonstrated a potential
positive effect of metformin in reducing cancer incidence and mortality, there has been an …
positive effect of metformin in reducing cancer incidence and mortality, there has been an …
Targeting lipid metabolism in metastatic prostate cancer
Despite key advances in the treatment of prostate cancer (PCa), a proportion of men have
de novo resistance, and all will develop resistance to current therapeutics over time …
de novo resistance, and all will develop resistance to current therapeutics over time …
Cancer-associated fibroblast-secreted glucosamine alters the androgen biosynthesis program in prostate cancer via HSD3B1 upregulation
After androgen deprivation, prostate cancer frequently becomes castration resistant (CRPC),
with intratumoral androgen production from extragonadal precursors that activate the …
with intratumoral androgen production from extragonadal precursors that activate the …
Nutrition, physical activity, and lifestyle factors in prostate cancer prevention
E Ballon-Landa, JK Parsons - Current opinion in urology, 2018 - journals.lww.com
Nutrition, physical activity, and lifestyle factors in prost... : Current Opinion in Urology Nutrition,
physical activity, and lifestyle factors in prostate cancer prevention : Current Opinion in Urology …
physical activity, and lifestyle factors in prostate cancer prevention : Current Opinion in Urology …
Why exercise has a crucial role in cancer prevention, risk reduction and improved outcomes
R Thomas, SA Kenfield, Y Yanagisawa… - British medical …, 2021 - academic.oup.com
Introduction Exercise is one of several factors known to lower the risk of develo** cancer,
as well as improve outcomes in patients already diagnosed. People who exercise after …
as well as improve outcomes in patients already diagnosed. People who exercise after …
Metformin in chemotherapy-naive castration-resistant prostate cancer: a multicenter phase 2 trial (SAKK 08/09)
Background There is evidence linking metformin to improved prostate cancer (PCa)-related
outcomes. Objective To evaluate treatment with metformin in patients with castration …
outcomes. Objective To evaluate treatment with metformin in patients with castration …