The interaction of cells within their microenvironmental niche is fundamental to cell
migration, positioning, growth and differentiation in order to form and maintain complex …

In this paper, we review spatial light interference microscopy (SLIM), a common-path, phase-
shifting interferometer, built onto a phase-contrast microscope, with white-light illumination …

The histological analysis of tissue samples, widely used for disease diagnosis, involves
lengthy and laborious tissue preparation. Here, we show that a convolutional neural network …

Multiphoton fluorescence microscopy is a powerful technique for deep-tissue observation of
living cells. In particular, three-photon microscopy is highly beneficial for deep-tissue …

Surgery is an essential component in the treatment of brain tumors. However, delineating
tumor from normal brain remains a major challenge. We describe the use of stimulated …

Cancer cell invasion is an adaptive process based on cell-intrinsic properties to migrate
individually or collectively, and their adaptation to encountered tissue structure acting as …

The preparation, staining, visualization and interpretation of histological images of tissue is
well accepted as the gold standard process for the diagnosis of disease. These methods …

Nonlinear optical microscopy has become a powerful tool in bioimaging research due to its
unique capabilities of deep optical sectioning, high‐spatial‐resolution imaging, and 3D …

Differentiating tumor from normal brain is a major barrier to achieving optimal outcome in
brain tumor surgery. New imaging techniques for visualizing tumor margins during surgery …

We report a newly developed technique for high-resolution in vivo imaging of myelinated
axons in the brain, spinal cord and peripheral nerve that requires no fluorescent labeling …