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Biomedical and biochemical applications of self-assembled metallacycles and metallacages
Metal ions and metal complexes with organic molecules are ubiquitous in nature. Bulk metal
ions of Na, K, Mg, and Ca constitute as much as 1% of human body weight. The remaining …
ions of Na, K, Mg, and Ca constitute as much as 1% of human body weight. The remaining …
Recent developments of supramolecular metal-based structures for applications in cancer therapy and imaging
The biomedical application of discrete supramolecular metal-based structures, including
supramolecular coordination complexes (SCCs), is still an emergent field of study. However …
supramolecular coordination complexes (SCCs), is still an emergent field of study. However …
Metal–organic polyhedron capped with cucurbit [8] uril delivers doxorubicin to cancer cells
SK Samanta, D Moncelet, V Briken… - Journal of the American …, 2016 - ACS Publications
Self-assembly of ligand 1 and Pd (NO3) 2 delivers Fujita-type metal–organic polyhedron
(MOP) 3 which bears 24 covalently attached methyl viologen units on its external surface, as …
(MOP) 3 which bears 24 covalently attached methyl viologen units on its external surface, as …
Metal‐Modified Nucleic Acids: Metal‐Mediated Base Pairs, Triples, and Tetrads
The incorporation of metal ions into nucleic acids by means of metal‐mediated base pairs
represents a promising and prominent strategy for the site‐specific decoration of these self …
represents a promising and prominent strategy for the site‐specific decoration of these self …
Exploring the cellular accumulation of metal complexes
CA Puckett, RJ Ernst, JK Barton - Dalton Transactions, 2010 - pubs.rsc.org
Transition metal complexes offer great potential as diagnostic and therapeutic agents, and a
growing number of biological applications have been explored. To be effective, these …
growing number of biological applications have been explored. To be effective, these …
Optically pure, water-stable metallo-helical 'flexicate'assemblies with antibiotic activity
SE Howson, A Bolhuis, V Brabec, GJ Clarkson… - Nature …, 2012 - nature.com
The helicates—chiral assemblies of two or more metal atoms linked by short or relatively
rigid multidentate organic ligands—may be regarded as non-peptide mimetics of α-helices …
rigid multidentate organic ligands—may be regarded as non-peptide mimetics of α-helices …
Interactions of small molecules with DNA junctions
The four natural DNA bases (A, T, G and C) associate in base pairs (A= T and G≡ C),
allowing the attached DNA strands to assemble into the canonical double helix of DNA (or …
allowing the attached DNA strands to assemble into the canonical double helix of DNA (or …
A triangular platinum (II) multinuclear complex with cytotoxicity towards breast cancer stem cells
A Eskandari, A Kundu, S Ghosh… - Angewandte …, 2019 - Wiley Online Library
The preparation of multinuclear metal complexes offers a route to novel anticancer agents
and delivery systems. The potency of a novel triangular multinuclear complex containing …
and delivery systems. The potency of a novel triangular multinuclear complex containing …
'Click'to functionalise: synthesis, characterisation and enhancement of the physical properties of a series of exo-and endo-functionalised Pd 2 L 4 nanocages
The synthesis of self-assembled metallosupramolecular architectures has been of steadily
growing interest in recent years due to their diverse applications. Appending additional …
growing interest in recent years due to their diverse applications. Appending additional …
Asymmetric triplex metallohelices with high and selective activity against cancer cells
Small cationic amphiphilic α-helical peptides are emerging as agents for the treatment of
cancer and infection, but they are costly and display unfavourable pharmacokinetics. Helical …
cancer and infection, but they are costly and display unfavourable pharmacokinetics. Helical …