[HTML][HTML] Disorders of endogenous and exogenous antioxidants in neurological diseases

I Korczowska-Łącka, B Słowikowski, T Piekut, M Hurła… - Antioxidants, 2023 - mdpi.com
In diseases of the central nervous system, such as Alzheimer's disease (AD), Parkinson's
disease (PD), stroke, amyotrophic lateral sclerosis (ALS), Huntington's disease (HD), and …

[HTML][HTML] A comprehensive review of emerging trends and innovative therapies in epilepsy management

S Ghosh, JK Sinha, S Ghosh, H Sharma, R Bhaskar… - Brain Sciences, 2023 - mdpi.com
Epilepsy is a complex neurological disorder affecting millions worldwide, with a substantial
number of patients facing drug-resistant epilepsy. This comprehensive review explores …

Mitochondrial permeability transition, cell death and neurodegeneration

AY Baev, AY Vinokurov, EV Potapova, AV Dunaev… - Cells, 2024 - mdpi.com
Neurodegenerative diseases are chronic conditions occurring when neurons die in specific
brain regions that lead to loss of movement or cognitive functions. Despite the progress in …

Luteolin ameliorates pentetrazole-induced seizures through the inhibition of the TLR4/NF-κB signaling pathway

Y Cheng, Y Zhang, P Huang, Q Cheng, H Ding - Epilepsy Research, 2024 - Elsevier
Epilepsy represents a prevalent neurological disorder in the population, and the existing
antiepileptic drugs (AEDs) often fail to adequately control seizures. Inflammation is …

Cannabidiol modulates hippocampal genes involved in mitochondrial function, ribosome biogenesis, synapse organization, and chromatin modifications

JPD Machado, V de Almeida, AW Zuardi… - Acta …, 2024 - cambridge.org
Background: Cannabidiol (CBD) is one of the main cannabinoids present in Cannabis sativa
female flowers. Previous investigation has already provided insights into the CBD molecular …

GABA (γ-aminobutyric acid) enrichment and detection methods in cereals: Unlocking sustainable health benefits

T Tufail, HBU Ain, MS Virk, J Ashraf, Z Ahmed… - Food Chemistry, 2024 - Elsevier
Abstract Gamma-aminobutyric acid (GABA), a non-protein amino acid primarily
biosynthesized in cereals, is vital to the human neurological system. As the primary …

Unraveling the nexus of age, epilepsy, and mitochondria: exploring the dynamics of cellular energy and excitability

W **e, S Koppula, MB Kale, LS Ali… - Frontiers in …, 2024 - frontiersin.org
Epilepsy, a complex neurological condition marked by recurring seizures, is increasingly
recognized for its intricate relationship with mitochondria, the cellular powerhouses …

Flavonoids as therapeutic agents for epilepsy: Unveiling anti-inflammatory and antioxidant pathways for novel treatments

Y Zhang, X Hu, LQ Zou - Frontiers in Pharmacology, 2024 - frontiersin.org
Epilepsy, a chronic neurological disorder affecting millions globally, is often exacerbated by
neuroinflammation and oxidative stress. Existing antiepileptic drugs primarily manage …

The Gut-Brain Axis and Neuroinflammation in Traumatic Brain Injury

MO Oyovwi, OA Udi - Molecular Neurobiology, 2024 - Springer
Traumatic brain injury (TBI) is a major global disability and mortality cause, with the gut-brain
axis playing a crucial role in its pathophysiology. Neuroinflammation, triggered by microglia …

[HTML][HTML] Advancing neurological disorders therapies: Organic nanoparticles as a key to blood-brain barrier penetration

ZS Razavi, SS Alizadeh, FS Razavi, M Souri… - International Journal of …, 2025 - Elsevier
The blood–brain barrier (BBB) plays a vital role in protecting the central nervous system
(CNS) by preventing the entry of harmful pathogens from the bloodstream. However, this …