Mass spectrometry imaging and integration with other imaging modalities for greater molecular understanding of biological tissues

T Porta Siegel, G Hamm, J Bunch, J Cappell… - Molecular imaging and …, 2018 - Springer
Over the last two decades, mass spectrometry imaging (MSI) has been increasingly
employed to investigate the spatial distribution of a wide variety of molecules in complex …

Metal-based redox-responsive MRI contrast agents

SM Pinto, V Tomé, MJF Calvete, MMCA Castro… - Coordination Chemistry …, 2019 - Elsevier
Given their potential in a better characterization and diagnosis of major pathologies like
cancer or chronic inflammation, redox-activated Magnetic Resonance Imaging (MRI) probes …

Photodynamic therapy with targeted release of boron-dipyrromethene dye from cobalt (III) prodrugs in red light

A Jana, S Sahoo, S Paul, S Sahoo… - Inorganic …, 2024 - ACS Publications
Boron-dipyrromethene (BODIPY) dyes are promising photosensitizers for cellular imaging
and photodynamic therapy (PDT) owing to their excellent photophysical properties and the …

Discovery of thirteen cobalt (II) and copper (II) salicylaldehyde Schiff base complexes that induce apoptosis and autophagy in human lung adenocarcinoma A549/DDP …

YT Chen, SN Zhang, ZF Wang, QM Wei… - Dalton Transactions, 2022 - pubs.rsc.org
In this study, 13 transition metal complexes, namely,[Cu (L1H)(H2O) 2]·(H2O)· NO3 (1),[Cu
(LnH2) 2]·(NO3)·(H2O) 2 (2, n= 2; 3, n= 3; 4, n= 4; 5, n= 5),[Co (LnH) 2] 2·(H2O) 0.5 (6, n= 2; …

Redox-Responsive MRI Probes Based on First-Row Transition-Metal Complexes

JR Morrow, JJ Raymond, MSI Chowdhury… - Inorganic …, 2022 - ACS Publications
The presence of multiple oxidation and spin states of first-row transition-metal complexes
facilitates the development of switchable MRI probes. Redox-responsive probes capitalize …

Characterization of an aggregated three-dimensional cell culture model by multimodal mass spectrometry imaging

LE Flint, G Hamm, JD Ready, S Ling… - Analytical …, 2020 - ACS Publications
Mass spectrometry imaging (MSI) is an established analytical tool capable of defining and
understanding complex tissues by determining the spatial distribution of biological …

Tris (2-pyridylmethyl) amines as emerging scaffold in supramolecular chemistry

C Bravin, E Badetti, G Licini, C Zonta - Coordination Chemistry Reviews, 2021 - Elsevier
Abstract tris-(2-Pyridylmethyl) amine (usually abbreviated as TPA or TPMA) are ligands
which are emerging in many fields of chemistry because of their ability to form stable and …

Proton‐Induced Spin State Switching in an FeIII Complex

CT Kelly, S Dunne, IA Kühne, A Barker… - Angewandte …, 2023 - Wiley Online Library
Reversible proton‐induced spin state switching of an FeIII complex in solution is observed at
room temperature. A reversible magnetic response was detected in the complex,[FeIII …

Bioinspired small-molecule tools for the imaging of redox biology

A Kaur, EJ New - Accounts of Chemical Research, 2019 - ACS Publications
Conspectus The availability of electrons to biological systems underpins the mitochondrial
electron transport chain (ETC) that powers living cells. It is little wonder, therefore, that the …

[HTML][HTML] Dual-mode tumor imaging using probes that are responsive to hypoxia-induced pathological conditions

SAAS Subasinghe, RG Pautler, MAH Samee… - Biosensors, 2022 - mdpi.com
Hypoxia in solid tumors is associated with poor prognosis, increased aggressiveness, and
strong resistance to therapeutics, making accurate monitoring of hypoxia important. Several …