The role of vaccines in combatting antimicrobial resistance

F Micoli, F Bagnoli, R Rappuoli, D Serruto - Nature Reviews …, 2021‏ - nature.com
The use of antibiotics has enabled the successful treatment of bacterial infections, saving the
lives and improving the health of many patients worldwide. However, the emergence and …

Defining and combating antibiotic resistance from One Health and Global Health perspectives

S Hernando-Amado, TM Coque, F Baquero… - Nature …, 2019‏ - nature.com
Several interconnected human, animal and environmental habitats can contribute to the
emergence, evolution and spread of antibiotic resistance, and the health of these contiguous …

Uncovering the mechanisms of Acinetobacter baumannii virulence

CM Harding, SW Hennon, MF Feldman - Nature Reviews Microbiology, 2018‏ - nature.com
Acinetobacter baumannii is a nosocomial pathogen that causes ventilator-associated as
well as bloodstream infections in critically ill patients, and the spread of multidrug-resistant …

Programmed nanocloak of commensal bacteria-derived nanovesicles amplify strong immunoreactivity against tumor growth and metastatic progression

J Zhang, S Wan, H Zhou, J Du, Y Li, H Zhu, L Weng… - ACS …, 2024‏ - ACS Publications
Recent discoveries in commensal microbiota demonstrate the great promise of intratumoral
bacteria as attractive molecular targets of tumors in improving cancer treatment. However …

[HTML][HTML] The promising potential of reverse vaccinology-based next-generation vaccine development over conventional vaccines against antibiotic-resistant bacteria

K Khalid, CL Poh - Vaccines, 2023‏ - mdpi.com
The clinical use of antibiotics has led to the emergence of multidrug-resistant (MDR)
bacteria, leading to the current antibiotic resistance crisis. To address this issue, next …

The Prevalence of Multidrug-Resistant Acinetobacter baumannii and Its Vaccination Status among Healthcare Providers

A Elbehiry, E Marzouk, I Moussa, Y Mushayt… - Vaccines, 2023‏ - mdpi.com
There is growing concern among healthcare providers worldwide regarding the prevalence
of multidrug-resistant Acinetobacter baumannii (A. baumannii). Some of the worst hospital …

An unnatural amino acid dependent, conditional Pseudomonas vaccine prevents bacterial infection

M Pigula, YC Lai, M Koh, CS Diercks… - Nature …, 2024‏ - nature.com
Live vaccines are ideal for inducing immunity but suffer from the need to attenuate their
pathogenicity or replication to preclude the possibility of escape. Unnatural amino acids …

Vaccine development for bacterial pathogens: Advances, challenges and prospects

IE Mba, HC Sharndama… - Tropical Medicine & …, 2023‏ - Wiley Online Library
The advent and use of antimicrobials have played a key role in treating potentially life‐
threatening infectious diseases, improving health, and saving the lives of millions of people …

Emerging therapies against infections with Pseudomonas aeruginosa

B Tümmler - F1000Research, 2019‏ - pmc.ncbi.nlm.nih.gov
Infections with Pseudomonas aeruginosa have been marked with the highest priority for
surveillance and epidemiological research on the basis of parameters such as incidence …

Recent Advances in the Pursuit of an Effective Acinetobacter baumannii Vaccine

PS Gellings, AA Wilkins, LA Morici - Pathogens, 2020‏ - mdpi.com
Acinetobacter baumannii has been a major cause of nosocomial infections for decades. The
absence of an available vaccine coupled with emerging multidrug resistance has prevented …