Treatment-resistant depression revisited: a glimmer of hope
A Halaris, E Sohl, EA Whitham - Journal of personalized medicine, 2021 - mdpi.com
Major Depressive Disorder (MDD) is a highly prevalent psychiatric disorder worldwide. It
causes individual suffering, loss of productivity, increased health care costs and high suicide …
causes individual suffering, loss of productivity, increased health care costs and high suicide …
Ketamine's mechanism of action with an emphasis on neuroimmune regulation: can the complement system complement ketamine's antidepressant effects?
B Quintanilla, CA Zarate Jr, A Pillai - Molecular Psychiatry, 2024 - nature.com
Over 300 million people worldwide suffer from major depressive disorder (MDD).
Unfortunately, only 30–40% of patients with MDD achieve complete remission after …
Unfortunately, only 30–40% of patients with MDD achieve complete remission after …
Ultrasensitive Terahertz Biodetection Enabled by Quasi‐BIC‐Based Metasensors
Advanced sensing devices, highly sensitive, and reliable in detecting ultralow
concentrations of circulating biomarkers, are extremely desirable and hold great promise for …
concentrations of circulating biomarkers, are extremely desirable and hold great promise for …
Association of inflammation with depression and anxiety: evidence for symptom-specificity and potential causality from UK Biobank and NESDA cohorts
We examined whether inflammation is uniformly associated with all depressive and anxiety
symptoms, and whether these associations are potentially causal. Data was from 147,478 …
symptoms, and whether these associations are potentially causal. Data was from 147,478 …
Interleukin-6 as potential mediator of long-term neuropsychiatric symptoms of COVID-19
The majority of COVID-19 survivors experience long-term neuropsychiatric symptoms such
as fatigue, slee** difficulties, depression and anxiety. We propose that neuroimmune …
as fatigue, slee** difficulties, depression and anxiety. We propose that neuroimmune …
The future is dynamic: A call for intensive longitudinal data in immunopsychiatry
The long-term value of immunopsychiatry will be based on its ability to translate basic
science into effective clinical interventions. In this article, we discuss a key obstacle to …
science into effective clinical interventions. In this article, we discuss a key obstacle to …
Polygenic risk for immuno-metabolic markers and specific depressive symptoms: A multi-sample network analysis study
Background About every fourth patient with major depressive disorder (MDD) shows
evidence of systemic inflammation. Previous studies have shown inflammation-depression …
evidence of systemic inflammation. Previous studies have shown inflammation-depression …
Higher immune-related gene expression in major depression is independent of CRP levels: results from the BIODEP study
L Sforzini, A Cattaneo, C Ferrari, L Turner… - Translational …, 2023 - nature.com
Compelling evidence demonstrates that some individuals suffering from major depressive
disorder (MDD) exhibit increased levels of inflammation. Most studies focus on inflammation …
disorder (MDD) exhibit increased levels of inflammation. Most studies focus on inflammation …
A network analysis of depressive symptoms and metabolomics
BackgroundDepression is associated with metabolic alterations including lipid
dysregulation, whereby associations may vary across individual symptoms. Evaluating these …
dysregulation, whereby associations may vary across individual symptoms. Evaluating these …
[HTML][HTML] Personality pathways to mortality: Interleukin-6 links conscientiousness to mortality risk
Personality is associated consistently with mortality hazards, but the physiological pathways
are not yet clear. Immune system dysregulation may be one such pathway due to its role in …
are not yet clear. Immune system dysregulation may be one such pathway due to its role in …