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Finding the genomic basis of local adaptation: pitfalls, practical solutions, and future directions
Uncovering the genetic and evolutionary basis of local adaptation is a major focus of
evolutionary biology. The recent development of cost-effective methods for obtaining high …
evolutionary biology. The recent development of cost-effective methods for obtaining high …
Common garden experiments in the genomic era: new perspectives and opportunities
The study of local adaptation is rendered difficult by many evolutionary confounding
phenomena (for example, genetic drift and demographic history). When complex traits are …
phenomena (for example, genetic drift and demographic history). When complex traits are …
Comparing methods for detecting multilocus adaptation with multivariate genotype–environment associations
Identifying adaptive loci can provide insight into the mechanisms underlying local
adaptation. Genotype–environment association (GEA) methods, which identify these loci …
adaptation. Genotype–environment association (GEA) methods, which identify these loci …
pcadapt: an R package to perform genome scans for selection based on principal component analysis
The r package pcadapt performs genome scans to detect genes under selection based on
population genomic data. It assumes that candidate markers are outliers with respect to how …
population genomic data. It assumes that candidate markers are outliers with respect to how …
Genome-wide scan for adaptive divergence and association with population-specific covariates
M Gautier - Genetics, 2015 - academic.oup.com
In population genomics studies, accounting for the neutral covariance structure across
population allele frequencies is critical to improve the robustness of genome-wide scan …
population allele frequencies is critical to improve the robustness of genome-wide scan …
Evolutionary history and global spread of the Mycobacterium tuberculosis Bei**g lineage
Mycobacterium tuberculosis strains of the Bei**g lineage are globally distributed and are
associated with the massive spread of multidrug-resistant (MDR) tuberculosis in Eurasia …
associated with the massive spread of multidrug-resistant (MDR) tuberculosis in Eurasia …
The relative power of genome scans to detect local adaptation depends on sampling design and statistical method
Although genome scans have become a popular approach towards understanding the
genetic basis of local adaptation, the field still does not have a firm grasp on how sampling …
genetic basis of local adaptation, the field still does not have a firm grasp on how sampling …
Fast principal-component analysis reveals convergent evolution of ADH1B in Europe and East Asia
Searching for genetic variants with unusual differentiation between subpopulations is an
established approach for identifying signals of natural selection. However, existing methods …
established approach for identifying signals of natural selection. However, existing methods …
[HTML][HTML] The genomics of human local adaptation
Modern humans inhabit a variety of environments and are exposed to a plethora of selective
pressures, leading to multiple genetic adaptations to local environmental conditions. These …
pressures, leading to multiple genetic adaptations to local environmental conditions. These …
Using neutral, selected, and hitchhiker loci to assess connectivity of marine populations in the genomic era
Estimating the rate of exchange of individuals among populations is a central concern to
evolutionary ecology and its applications to conservation and management. For instance …
evolutionary ecology and its applications to conservation and management. For instance …