Hacking the host: exploitation of macrophage polarization by intracellular bacterial pathogens

JD Thiriot, YB Martinez-Martinez… - Pathogens and …, 2020 - academic.oup.com
Macrophages play an integral role in host defenses against intracellular bacterial
pathogens. A remarkable plasticity allows for adaptation to the needs of the host to …

[HTML][HTML] Coxiella burnetii: international pathogen of mystery

AL Dragan, DE Voth - Microbes and infection, 2020 - Elsevier
Coxiella burnetii is an intracellular bacterium that causes acute and chronic Q fever. This
unique pathogen has been historically challenging to study due to obstacles in genetically …

[HTML][HTML] Recent Advances on the Innate Immune Response to Coxiella burnetii

G Sireci, GD Badami, D Di Liberto, V Blanda… - Frontiers in Cellular …, 2021 - frontiersin.org
Coxiella burnetii is an obligate intracellular Gram-negative bacterium and the causative
agent of a worldwide zoonosis known as Q fever. The pathogen invades monocytes and …

Alveolar Macrophages Are Key Players in the Modulation of the Respiratory Antiviral Immunity Induced by Orally Administered Lacticaseibacillus rhamnosus …

V Garcia-Castillo, M Tomokiyo, F Raya Tonetti… - Frontiers in …, 2020 - frontiersin.org
The oral administration of Lacticaseibacillus rhamnosus CRL1505 differentially modulates
the respiratory innate antiviral immune response triggered by Toll-like receptor 3 (TLR3) …

Coxiella co-opts the Glutathione Peroxidase 4 to protect the host cell from oxidative stress–induced cell death

RK Loterio, DR Thomas, W Andrade, YW Lee… - Proceedings of the …, 2023 - pnas.org
The causative agent of human Q fever, Coxiella burnetii, is highly adapted to infect alveolar
macrophages by inhibiting a range of host responses to infection. Despite the clinical and …

Interaction between autophagic vesicles and the Coxiella-containing vacuole requires CLTC (clathrin heavy chain)

EA Latomanski, HJ Newton - Autophagy, 2018 - Taylor & Francis
Coxiella burnetii is an intracellular bacterial pathogen which causes Q fever, a human
infection with the ability to cause chronic disease with potentially life-threatening outcomes …

[HTML][HTML] The role of alveolar macrophages in the improved protection against respiratory syncytial virus and pneumococcal superinfection induced by the …

P Clua, M Tomokiyo, F Raya Tonetti, MA Islam… - Cells, 2020 - mdpi.com
The nasal priming with nonviable Lactobacillus rhamnosus CRL1505 (NV1505) or its
purified peptidoglycan (PG1505) differentially modulates the respiratory innate immune …

[HTML][HTML] Immunobiotic Ligilactobacillus salivarius FFIG58 Confers Long-Term Protection against Streptococcus pneumoniae

M Elean, F Raya Tonetti, K Fukuyama… - International Journal of …, 2023 - mdpi.com
Previously, we isolated potentially probiotic Ligilactobacillus salivarius strains from the
intestines of wakame-fed pigs. The strains were characterized based on their ability to …

Embracing multiple infection models to tackle Q fever: a review of in vitro, in vivo, and lung ex vivo models

RM Guzman, DE Voth - Cellular Immunology, 2024 - Elsevier
Multiple animal and cell culture models are employed to study pathogenesis of Coxiella
burnetii, the causative agent of acute and chronic human Q fever. C. burnetii is a lung …

Coxiella burnetii intratracheal aerosol infection model in mice, guinea pigs, and nonhuman primates

AE Gregory, EJ Van Schaik… - Infection and …, 2019 - journals.asm.org
Coxiella burnetii, the etiological agent of Q fever, is a Gram-negative bacterium transmitted
to humans by inhalation of contaminated aerosols. Acute Q fever is often self-limiting …