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Ferroptosis: mechanisms and links with diseases
Ferroptosis is an iron-dependent cell death, which is different from apoptosis, necrosis,
autophagy, and other forms of cell death. The process of ferroptotic cell death is defined by …
autophagy, and other forms of cell death. The process of ferroptotic cell death is defined by …
Ferroptosis at the crossroads of cancer-acquired drug resistance and immune evasion
Ferroptosis is a recently recognized cell death modality that is morphologically,
biochemically and genetically distinct from other forms of cell death and that has emerged to …
biochemically and genetically distinct from other forms of cell death and that has emerged to …
Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death
Ferroptotic death is the penalty for losing control over three processes—iron metabolism,
lipid peroxidation and thiol regulation—that are common in the pro-inflammatory …
lipid peroxidation and thiol regulation—that are common in the pro-inflammatory …
Diversity of macrophages in lung homeostasis and diseases
F Hou, K **ao, L Tang, L **e - Frontiers in immunology, 2021 - frontiersin.org
Lung macrophages play important roles in the maintenance of homeostasis, pathogen
clearance and immune regulation. The different types of pulmonary macrophages and their …
clearance and immune regulation. The different types of pulmonary macrophages and their …
Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis
Enigmatic lipid peroxidation products have been claimed as the proximate executioners of
ferroptosis—a specialized death program triggered by insufficiency of glutathione …
ferroptosis—a specialized death program triggered by insufficiency of glutathione …
Linking cellular stress responses to systemic homeostasis
Mammalian cells respond to stress by activating mechanisms that support cellular functions
and hence maintain microenvironmental and organismal homeostasis. Intracellular …
and hence maintain microenvironmental and organismal homeostasis. Intracellular …
The role of efferocytosis‐fueled macrophage metabolism in the resolution of inflammation
The phagocytosis of dying cells by macrophages, termed efferocytosis, is a tightly regulated
process that involves the sensing, binding, engulfment, and digestion of apoptotic cells …
process that involves the sensing, binding, engulfment, and digestion of apoptotic cells …
Resolution of chronic inflammatory disease: universal and tissue-specific concepts
G Schett, MF Neurath - Nature communications, 2018 - nature.com
Inflammation and its resolution is under-studied in medicine despite being essential for
understanding the development of chronic inflammatory disease. In this review article, we …
understanding the development of chronic inflammatory disease. In this review article, we …
Resolution of inflammation: a new therapeutic frontier
JN Fullerton, DW Gilroy - Nature reviews Drug discovery, 2016 - nature.com
Dysregulated inflammation is a central pathological process in diverse disease states.
Traditionally, therapeutic approaches have sought to modulate the pro-or anti-inflammatory …
Traditionally, therapeutic approaches have sought to modulate the pro-or anti-inflammatory …
[HTML][HTML] PEBP1 wardens ferroptosis by enabling lipoxygenase generation of lipid death signals
Ferroptosis is a form of programmed cell death that is pathogenic to several acute and
chronic diseases and executed via oxygenation of polyunsaturated …
chronic diseases and executed via oxygenation of polyunsaturated …