Uterine leiomyomas are benign tumors that originate from the myometrium. Evidence points
to ovarian steroid hormones, in particular, progesterone as major promoters of leiomyoma …

OBJECTIVE: To summarize the information regarding pathogenetic factors of leiomyoma
formation and growth, and to make a simple integrated pathogenetic view of this tumor for …

Uterine leiomyomas (fibroids) are the most common benign tumors in women of
reproductive age. These tumors are three to four times more prevalent in African American …

Purpose Currently there is no effective medicinal treatment for uterine fibroids (UFs), a
common health disorder that affects women of reproductive age. Identification of modifiable …

Background It is well established that tumors are dependent on angiogenesis for their
growth and survival. Although uterine fibroids are known to be benign tumors with reduced …

OBJECTIVE: To evaluate the effects and mechanisms of action of vitamin D on human
uterine leiomyoma (HuLM) cell proliferation in vitro. DESIGN: Laboratory study. SETTING …

Uterine fibroids (leiomyomata) are extremely common lesions that are associated with
detrimental effects including infertility and abnormal uterine bleeding. Fibroids cause …

Uterine fibroids (UFs) remain a significant health issue for many women, with a
disproportionate impact on women of color, likely due to both genetic and environmental …

Highlights•Medical management should be considered as an alternative to surgery in the
management of fibroids.•Selection of medical management should be based on a patient's …

The purpose of the National Institutes of Health conference Fibroid Research Workshop in
September 2007 was to bring Eunice Kennedy Shriver National Institute of Child Health and …