Oxidative stress (OS), defined as redox imbalance in favor of oxidant burden, is one of the
most significant biological events in cancer progression. Cancer cells generally represent a …

Colorectal cancer (CRC) is one of the most common malignant carcinomas. CRC is
characterized by asymptomatic onset, and most patients are already in the middle and …

fluorouracil (5-FU) is an efficacious fluoropyrimidine antimetabolite anticancer drug,
however, its clinical utility is constrained due to side effect toxicity on delicate organs …

Background In the present study, the poncirin which is flavonoid-7-o-glycosides (isolated
from the Poncirus trifoliata) in nature was evaluated against the Carbon tetra chloride …

Aim: To fabricate and evaluate curcumin-loaded transfersomes (Cur-TF) for the targeted
delivery and enhanced therapeutic efficacy of curcumin for the treatment of rheumatoid …

Acute or chronic liver injury is associated with hyperammonemia which induced
neuroinflammation and oxidative stress in the brain. Neuroinflammation, oxidative stress …

Background Acute lung injury (ALI) together with acute respiratory distress syndrome
(ARDS) are associated with high rate of mortality and morbidity in patients. In the current …

Herbal drugs have been attracting much scientific interest in the last few decades and
nowadays, phytoconstituents-based research is in progress to disclose their unidentified …

Vincristine (VCR) is a widely used chemotherapy drug that induced peripheral painful
neuropathy. Yet, it still lacks an ideal therapeutic strategy. The transient receptor potential …

The present study aimed to fabricate and evaluate the therapeutic efficacy of pH-responsive
Ibuprofen (IB) nanoparticles (NPs) loaded transdermal hydrogel against rheumatoid arthritis …