The application of nanotechnology concepts to medicine joins two large cross‐disciplinary
fields with an unprecedented societal and economical potential arising from the natural …

Progress in the application of the atomic force microscope (AFM) to imaging and
manipulating biomolecules is the result of improved instrumentation, sample preparation …

We describe the fluidFM, an atomic force microscope (AFM) based on hollow cantilevers for
local liquid dispensing and stimulation of single living cells under physiological conditions. A …

Ever since the genesis of life, and throughout the course its further evolution, Nature has
constantly been called upon to act as an engineer in solving technical problems. Organisms …

Many biologists have dreamt of physically touching and manipulating the biomolecules they
were investigating. With the invention of the atomic force microscope (AFM), this dream has …

▪ Abstract The atomic force microscope operates on surfaces. Since surfaces occupy much
of the space in living organisms, surface biology is a valid and valuable form of biology that …

Diatoms generate their cell walls by silica biomineralization. The cell walls are composed of
silica and organic macromolecules and show a complex microscopic structure. Analysis of …

The combination of biology and nanotechnology has led to a new generation of
nanodevices that make it possible to characterize the chemical, mechanical, and other …

A current challenge in the life sciences is to understand how the properties of individual
molecular machines adjust in order to meet the functional requirements of the cell. Recent …

We present a custom‐designed atomic force fluorescence microscope (AFFM), which can
perform simultaneous optical and topographic measurements with single molecule …