Advances in aptamer-mediated targeted delivery system for cancer treatment

S He, Y Du, H Tao, H Duan - International Journal of Biological …, 2023 - Elsevier
Aptamers with high affinity and specificity for certain targets have rapidly become a novel
class of targeted ligands applicated in drug delivery. Based on the excellent characteristics …

[HTML][HTML] Paclitaxel and docetaxel resistance in prostate cancer: Molecular mechanisms and possible therapeutic strategies

M Hashemi, MA Zandieh, Y Talebi… - Biomedicine & …, 2023 - Elsevier
Prostate cancer is among most malignant tumors around the world and this urological tumor
can be developed as result of genomic mutations and their accumulation during progression …

Recent advances in the targeted delivery of paclitaxel nanomedicine for cancer therapy

F Raza, H Zafar, MW Khan, A Ullah, AU Khan… - Materials …, 2022 - pubs.rsc.org
Cancer cases have reached an all-time high in the current era. Thus, there is a need to
develop advanced therapeutic methods that can effectively inhibit the proliferation of …

Molecular panorama of therapy resistance in prostate cancer: a pre-clinical and bioinformatics analysis for clinical translation

M Ashrafizadeh, W Zhang, Y Tian, G Sethi… - Cancer and Metastasis …, 2024 - Springer
Prostate cancer (PCa) is a malignant disorder of prostate gland being asymptomatic in early
stages and high metastatic potential in advanced stages. The chemotherapy and surgical …

Diethyldithiocarbamate copper nanoparticle overcomes resistance in cancer therapy without inhibiting P-glycoprotein

X Kang, J Wang, CH Huang, FS Wibowo… - … , Biology and Medicine, 2023 - Elsevier
Abstract Copper diethyldithiocarbamate [Cu (DDC) 2] is a promising anticancer agent.
However, its poor water solubility is a significant obstacle to clinical application. In previous …

βIII-tubulin overexpression in cancer: Causes, consequences, and potential therapies

A Kanakkanthara, JH Miller - Biochimica et Biophysica Acta (BBA)-Reviews …, 2021 - Elsevier
Class III β-tubulin (βIII-tubulin) is frequently overexpressed in human tumors and is
associated with resistance to microtubule-targeting agents, tumor aggressiveness, and poor …

[HTML][HTML] Active ingredients from Chinese medicine for combination cancer therapy

X Wang, J Li, R Chen, T Li, M Chen - International Journal of …, 2023 - ncbi.nlm.nih.gov
Combination therapy against cancer has gained increasing attention because it can help to
target multiple pathways to tackle oncologic progression and improve the limited antitumor …

Synergistic potential of nanomedicine in prostate cancer immunotherapy: breakthroughs and prospects

Y Jiang, C Wang, C Zu, X Rong, Q Yu… - International Journal of …, 2024 - Taylor & Francis
Given the global prevalence of prostate cancer in men, it is crucial to explore more effective
treatment strategies. Recently, immunotherapy has emerged as a promising cancer …

[HTML][HTML] Aptamers against cancer drug resistance: Small fighters switching tactics in the face of defeat

M Sanati, AR Afshari, SS Ahmadi, P Kesharwani… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Discovering novel cancer therapies has attracted extreme interest in the last decade. In this
regard, multidrug resistance (MDR) to chemotherapies is a key challenge in cancer …

Cabazitaxel‐Loaded Thermosensitive Hydrogel System for Suppressed Orthotopic Colorectal Cancer and Liver Metastasis

Y Chen, L Dai, K Shi, M Pan, L Yuan… - Advanced …, 2024 - Wiley Online Library
The treatment of colorectal cancer is always a major challenge in the field of cancer
research. The number of estimated new cases of colorectal cancer worldwide in 2020 is 1 …