Calcium ions generate versatile intracellular signals that control key functions in all types of
neurons. Imaging calcium in neurons is particularly important because calcium signals exert …

Advances in optical manipulation and observation of neural activity have set the stage for
widespread implementation of closed-loop and activity-guided optical control of neural …

Calcium imaging with protein-based indicators, is widely used to follow neural activity in
intact nervous systems, but current protein sensors report neural activity at timescales much …

We present a modular approach for analyzing calcium imaging recordings of large neuronal
ensembles. Our goal is to simultaneously identify the locations of the neurons, demix …

Fundamentals of Brain Network Analysis is a comprehensive and accessible introduction to
methods for unraveling the extraordinary complexity of neuronal connectivity. From the …

The combination of two-photon microscopy recordings and powerful calcium-dependent
fluorescent sensors enables simultaneous recording of unprecedentedly large populations …

Advances in fluorescence microscopy enable monitoring larger brain areas in-vivo with finer
time resolution. The resulting data rates require reproducible analysis pipelines that are …

In vivo calcium imaging through microendoscopic lenses enables imaging of previously
inaccessible neuronal populations deep within the brains of freely moving animals …

Neural responses are modulated by brain state, which varies with arousal, attention, and
behavior. In mice, running and whisking desynchronize the cortex and enhance sensory …

Fluorescent calcium indicators are a popular means for observing the spiking activity of
large neuronal populations, but extracting the activity of each neuron from raw fluorescence …