Duchenne muscular dystrophy (DMD) is a severe, progressive disease that affects 1 in 3600–
6000 live male births. Although guidelines are available for various aspects of DMD …

Optimum management of Duchenne muscular dystrophy (DMD) requires a multidisciplinary
approach that focuses on anticipatory and preventive measures as well as active …

The complexity of central breathing disturbances during sleep has become increasingly
obvious. They present as central sleep apnoeas (CSAs) and hypopnoeas, periodic …

The muscular dystrophies are inherited myogenic disorders characterised by progressive
muscle wasting and weakness of variable distribution and severity. They can be subdivided …

Duchenne Muscular Dystrophy (DMD) is the most common muscle disease in children.
Historically, DMD results in loss of ambulation between ages 7 and 13 years and death in …

INTRODUCTION Clinical context and need for a guideline Neuromuscular diseases as a
group are relatively common with a prevalence of about 1 in 3000. The majority of these …

Noninvasive ventilation refers to the delivery of mechanical ventilation to the lungs using
techniques that do not require an endotracheal airway. During the first half of the 20th …

We reviewed the notes of 197 patients with Duchenne muscular dystrophy whose treatment
was managed at the Newcastle muscle centre from 1967 to 2002, to determine whether …

The act of breathing depends on coordinated activity of the respiratory muscles to generate
subatmospheric pressure. This action is compromised by disease states affecting …

Background Mutations that disrupt the open reading frame and prevent full translation of
DMD, the gene that encodes dystrophin, underlie the fatal X-linked disease Duchenne …