Medicinal plants and phytochemicals against multidrug-resistant tumor cells expressing ABCB1, ABCG2, or ABCB5: a synopsis of 2 decades
T Efferth, O Kadioglu, MEM Saeed, EJ Seo… - Phytochemistry …, 2021 - Springer
Multidrug resistance is a major factor causing the failure of cancer chemotherapy. Efflux
pumps of the ATP-binding cassette (ABC) transporter family expel a large array of diverse …
pumps of the ATP-binding cassette (ABC) transporter family expel a large array of diverse …
Cytotoxicity of the methanol extracts and compounds of Brucea antidysenterica (Simaroubaceae) towards multifactorial drug-resistant human cancer cell lines
LM Youmbi, YSD Makong, AT Mbaveng… - … Medicine and Therapies, 2023 - Springer
Background Cancer remains a global health concern and constitutes an important barrier to
increasing life expectancy. Malignant cells rapidly develop drug resistance leading to many …
increasing life expectancy. Malignant cells rapidly develop drug resistance leading to many …
Botanicals and phytochemicals from the bark of Hypericum roeperianum (Hypericaceae) had strong antibacterial activity and showed synergistic effects with …
OMF Demgne, F Damen, AG Fankam… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Infections due to multidrug-resistant (MDR) bacteria
constitute a real problem in the public health worldwide. Hypericum roeperianum Schimp. ex …
constitute a real problem in the public health worldwide. Hypericum roeperianum Schimp. ex …
Cytotoxic phytochemicals from the crude extract of Tetrapleura tetraptera fruits towards multi-factorial drug resistant cancer cells
Ethnopharmacological relevance Tetrapleura tetraptera is an African medicinal spice used
in traditional medicine to treat several ailments including cancer. Aim of the study The …
in traditional medicine to treat several ailments including cancer. Aim of the study The …
Sesquiterpene Lactones from Vernonia tufnelliae: Structural Characterization and Biological Evaluation
GTM Bitchagno, A Schüffler, J Gross… - Journal of Natural …, 2022 - ACS Publications
The genus Vernonia is an extremely rich source of biologically active sesquiterpene
lactones. The present report describes the spectroscopic structure elucidation and the …
lactones. The present report describes the spectroscopic structure elucidation and the …
The alkaloid, soyauxinium chloride, displays remarkable cytotoxic effects towards a panel of cancer cells, inducing apoptosis, ferroptosis and necroptosis
AT Mbaveng, CGT Noulala, ARM Samba… - Chemico-biological …, 2021 - Elsevier
The cytotoxic potential of a naturally occurring indoloquinazoline alkaloid, soyauxinium
chloride (SCHL), was determined on a broad panel of animal and human cancer cell lines …
chloride (SCHL), was determined on a broad panel of animal and human cancer cell lines …
Bioactivity of fractions and constituents of Piper capense fruits towards a broad panel of cancer cells
AT Mbaveng, BEN Wamba, GTM Bitchagno… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Piper capense is a medicinal spice whose fruits are
traditionally used as aqueous decoction to heal several ailments such as trypanosomiasis …
traditionally used as aqueous decoction to heal several ailments such as trypanosomiasis …
Cytotoxicity of botanicals and isolated phytochemicals from Araliopsis soyauxii Engl.(Rutaceae) towards a panel of human cancer cells
AT Mbaveng, CGT Noulala, ARM Samba… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Araliopsis soyauxii Engl.(Rutaceae) is a
Cameroonian medicinal plant traditionally used to treat lung diseases, malaria, and …
Cameroonian medicinal plant traditionally used to treat lung diseases, malaria, and …
Investigation of the influence of chirality and halogen atoms on the anticancer activity of enantiopure palladium (II) complexes derived from chiral amino-alcohol Schiff …
In continuation of our work on the synthesis of heteroleptic enantiopure Pd (II)-complexes,
four mixed-ligand enantiomeric pairs of Pd (II) complexes (J1–J8),[Pd (pic)(R or S)-N-(2, 3 …
four mixed-ligand enantiomeric pairs of Pd (II) complexes (J1–J8),[Pd (pic)(R or S)-N-(2, 3 …
Potential antibacterial pharmaceuticals from the flora of Africa
The present chapter highlights the antibacterial potential of nine highly active compounds
isolated from the African medicinal plants: 8, 8-bis-(dihydroconiferyl)-diferulate, buesgenine …
isolated from the African medicinal plants: 8, 8-bis-(dihydroconiferyl)-diferulate, buesgenine …