1,000 ancient genomes uncover 10,000 years of natural selection in Europe

MK Le, OS Smith, A Akbari, A Harpak, D Reich… - …, 2022 - pmc.ncbi.nlm.nih.gov
Ancient DNA has revolutionized our understanding of human population history. However,
its potential to examine how rapid cultural evolution to new lifestyles may have driven …

Models based on best-available information support a low inbreeding load and potential for recovery in the vaquita

CC Kyriazis, JA Robinson, SF Nigenda-Morales… - Heredity, 2023 - nature.com
In Robinson et al.(2022), we employed genomic and simulation analyses to demonstrate
that the critically endangered vaquita porpoise has a reduced potential for future inbreeding …

Emergence and influence of sequence bias in evolutionarily malleable, mammalian tandem arrays

MV Brovkina, MA Chapman, ML Holding, EJ Clowney - BMC biology, 2023 - Springer
Background The radiation of mammals at the extinction of the dinosaurs produced a
plethora of new forms—as diverse as bats, dolphins, and elephants—in only 10–20 million …

Background Selection From Unlinked Sites Causes Nonindependent Evolution of Deleterious Mutations

J Matheson, J Masel - Genome Biology and Evolution, 2024 - academic.oup.com
Background selection describes the reduction in neutral diversity caused by selection
against deleterious alleles at other loci. It is typically assumed that the purging of deleterious …