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Modulating the polarization phenotype of microglia–a valuable strategy for central nervous system diseases
Y Long, X Li, J Deng, Q Ye, D Li, Y Ma, Y Wu… - Ageing research …, 2024 - Elsevier
Central nervous system (CNS) diseases have become one of the leading causes of death in
the global population. The pathogenesis of CNS diseases is complicated, so it is important …
the global population. The pathogenesis of CNS diseases is complicated, so it is important …
TAM family kinases as therapeutic targets at the interface of cancer and immunity
D DeRyckere, JM Huelse, HS Earp… - Nature Reviews Clinical …, 2023 - nature.com
Novel treatment approaches are needed to overcome innate and acquired mechanisms of
resistance to current anticancer therapies in cancer cells and the tumour immune …
resistance to current anticancer therapies in cancer cells and the tumour immune …
Annexin A1 protects against cerebral ischemia–reperfusion injury by modulating microglia/macrophage polarization via FPR2/ALX-dependent AMPK-mTOR pathway
X Xu, W Gao, L Li, J Hao, B Yang, T Wang, L Li… - Journal of …, 2021 - Springer
Background Cerebral ischemia–reperfusion (I/R) injury is a major cause of early
complications and unfavorable outcomes after endovascular thrombectomy (EVT) therapy in …
complications and unfavorable outcomes after endovascular thrombectomy (EVT) therapy in …
Biomimetic Self‐Propelled Asymmetric Nanomotors for Cascade‐Targeted Treatment of Neurological Inflammation
The precise targeted delivery of therapeutic agents to deep regions of the brain is crucial for
the effective treatment of various neurological diseases. However, achieving this goal is …
the effective treatment of various neurological diseases. However, achieving this goal is …
Pembrolizumab and cabozantinib in recurrent metastatic head and neck squamous cell carcinoma: a phase 2 trial
NF Saba, CE Steuer, A Ekpenyong, A McCook-Veal… - Nature medicine, 2023 - nature.com
Anti-programmed cell death protein 1 (PD-1) therapy is a standard of care in recurrent
metastatic head and neck squamous cell carcinoma (RMHNSCC). Vascular endothelial …
metastatic head and neck squamous cell carcinoma (RMHNSCC). Vascular endothelial …
DKK3 ameliorates neuropathic pain via inhibiting ASK-1/JNK/p-38-mediated microglia polarization and neuroinflammation
LQ Zhang, SJ Gao, J Sun, DY Li, JY Wu… - Journal of …, 2022 - Springer
Background Neuropathic pain is a common and severely disabling state that affects millions
of people worldwide. Microglial activation in the spinal cord plays a critical role in the …
of people worldwide. Microglial activation in the spinal cord plays a critical role in the …
Anti-inflammatory mechanisms of neutrophil membrane-coated nanoparticles without drug loading
Q Zhang, C Hu, J Feng, H Long, Y Wang… - Journal of Controlled …, 2024 - Elsevier
Neutrophil membrane-coated nanoparticles (NM-NPs) are nanomedicines with traits of
mimicking the surface properties and functions of neutrophils, which are the most abundant …
mimicking the surface properties and functions of neutrophils, which are the most abundant …
Self-healing hydrogel as an injectable implant: translation in brain diseases
J Xu, S Hsu - Journal of Biomedical Science, 2023 - Springer
Tissue engineering biomaterials are aimed to mimic natural tissue and promote new tissue
formation for the treatment of impaired or diseased tissues. Highly porous biomaterial …
formation for the treatment of impaired or diseased tissues. Highly porous biomaterial …
Oroxin A alleviates early brain injury after subarachnoid hemorrhage by regulating ferroptosis and neuroinflammation
J Chen, Z Shi, C Zhang, K **ong, W Zhao… - Journal of …, 2024 - Springer
Background Subarachnoid hemorrhage (SAH), a severe subtype of stroke, is characterized
by notably high mortality and morbidity, largely due to the lack of effective therapeutic …
by notably high mortality and morbidity, largely due to the lack of effective therapeutic …
Neuroinflammation following traumatic brain injury: take it seriously or not
R Zheng, K Lee, Z Qi, Z Wang, Z Xu, X Wu… - Frontiers in …, 2022 - frontiersin.org
Traumatic brain injury (TBI) is associated with high mortality and disability, with a substantial
socioeconomic burden. With the standardization of the treatment process, there is increasing …
socioeconomic burden. With the standardization of the treatment process, there is increasing …