Traumatic brain injury: progress and challenges in prevention, clinical care, and research

AIR Maas, DK Menon, GT Manley, M Abrams… - The Lancet …, 2022 - thelancet.com
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation

JAHR Claassen, DHJ Thijssen… - Physiological …, 2021 - journals.physiology.org
Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …

Targeting autoregulation-guided cerebral perfusion pressure after traumatic brain injury (COGiTATE): a feasibility randomized controlled clinical trial

J Tas, E Beqiri, RC van Kaam, M Czosnyka… - Journal of …, 2021 - liebertpub.com
Managing traumatic brain injury (TBI) patients with a cerebral perfusion pressure (CPP) near
to the cerebral autoregulation (CA)-guided “optimal” CPP (CPPopt) value is associated with …

Severe traumatic brain injury: targeted management in the intensive care unit

N Stocchetti, M Carbonara, G Citerio, A Ercole… - The Lancet …, 2017 - thelancet.com
Severe traumatic brain injury (TBI) is currently managed in the intensive care unit with a
combined medical–surgical approach. Treatment aims to prevent additional brain damage …

Pediatric traumatic brain injury: characteristic features, diagnosis, and management

T Araki, H Yokota, A Morita - Neurologia medico-chirurgica, 2017 - jstage.jst.go.jp
Traumatic brain injury (TBI) is the leading cause of death and disability in children. Pediatric
TBI is associated with several distinctive characteristics that differ from adults and are …

Cerebral blood flow autoregulation and dysautoregulation

WM Armstead - Anesthesiology clinics, 2016 - pmc.ncbi.nlm.nih.gov
The aim of this article is to provide an up-to-date review of the state-of-the-art in cerebral
autoregulation, particularly as it may relate to the clinician scientist whose expertise is in the …

Consensus summary statement of the international multidisciplinary consensus conference on multimodality monitoring in neurocritical care: a statement for …

P Le Roux, DK Menon, G Citerio, P Vespa, MK Bader… - Neurocritical care, 2014 - Springer
Neurocritical care depends, in part, on careful patient monitoring but as yet there are little
data on what processes are the most important to monitor, how these should be monitored …

Moderate and severe traumatic brain injury

CP Robinson - Continuum: lifelong learning in neurology, 2021 - journals.lww.com
PURPOSE OF REVIEW Traumatic brain injury (TBI) encompasses a group of
heterogeneous manifestations of a disease process with high neurologic morbidity and, for …

Translational research in traumatic brain injury

D Laskowitz, G Grant - 2016 - books.google.com
Traumatic brain injury (TBI) remains a significant source of death and permanent disability,
contributing to nearly one-third of all injury related deaths in the United States and exacting …

[HTML][HTML] Management of severe traumatic brain injury (first 24 hours)

T Geeraerts, L Velly, L Abdennour, K Asehnoune… - … Critical Care & Pain …, 2018 - Elsevier
Abstract The latest French Guidelines for the management in the first 24 hours of patients
with severe traumatic brain injury (TBI) were published in 1998. Due to recent changes …