Role of neurotrophins in pregnancy and offspring brain development

A Sahay, A Kale, S Joshi - Neuropeptides, 2020 - Elsevier
Neurotrophins are a family of functionally and structurally related proteins which play a key
role in the survival, development, and function of neurons in both the central and peripheral …

Developmental origins of adult health and disease: The metabolic role of BDNF from early life to adulthood

DD Briana, A Malamitsi-Puchner - Metabolism, 2018 - Elsevier
Accumulating evidence suggests that the origins of adult disease may occur during fetal life.
Thus, the concept of “developmental programming” has been introduced and supported by …

BNDF methylation in mothers and newborns is associated with maternal exposure to war trauma

DA Kertes, SS Bhatt, HS Kamin, DA Hughes… - Clinical …, 2017 - Springer
Background The BDNF gene codes for brain-derived neurotrophic factor, a growth factor
involved in neural development, cell differentiation, and synaptic plasticity. Present in both …

Brain-derived neurotrophic factor (BDNF) expression and function in the mammalian reproductive Tract

R Chow, JM Wessels, WG Foster - Human Reproduction Update, 2020 - academic.oup.com
BACKGROUND Neurotrophins of the nerve growth factor family are soluble polypeptides
that are best known for their role in nerve growth, survival and differentiation in the central …

Diet-induced obesity alters the maternal metabolome and early placenta transcriptome and decreases placenta vascularity in the mouse

TJ Stuart, K O'Neill, D Condon, I Sasson… - Biology of …, 2018 - academic.oup.com
Maternal obesity is associated with an increased risk of obesity and metabolic disease in
offspring. Increasing evidence suggests that the placenta plays an active role in fetal …

Neurotrophins: role in placental growth and development

AS Sahay, DP Sundrani, SR Joshi - Vitamins and hormones, 2017 - Elsevier
Neurotrophins, a family of closely related proteins, were originally identified as growth
factors for survival, development, and function of neurons in both the central and peripheral …

Placental CpG methylation of HPA-axis genes is associated with cognitive impairment at age 10 among children born extremely preterm

CJ Meakin, EM Martin, HP Santos Jr, I Mokrova… - Hormones and …, 2018 - Elsevier
Placental CpG methylation of HPA-axis genes is associated with cognitive impairment at age 10
among children born extremely preterm - ScienceDirect Skip to main contentSkip to article …

Serum brain-derived neurotrophic factor (BDNF) across pregnancy and postpartum: associations with race, depressive symptoms, and low birth weight

LM Christian, AM Mitchell, SL Gillespie… - …, 2016 - Elsevier
Background Brain-derived neurotrophic factor (BDNF) is implicated as a causal factor in
major depression and is critical to placental development during pregnancy. Longitudinal …

Determinants of brain-derived neurotrophic factor (BDNF) in umbilical cord and maternal serum

A Flöck, SK Weber, N Ferrari, C Fietz, C Graf… - …, 2016 - Elsevier
Objective Brain-derived neurotrophic factor (BDNF) plays a fundamental role in brain
development; additionally, it is involved in various aspects of cerebral function, including …

Maternal epigenetic dysregulation as a possible risk factor for neurodevelopmental disorders

C Lintas, I Cassano, A Azzarà, MG Stigliano, C Gregorj… - Genes, 2023 - mdpi.com
Neurodevelopmental Disorders (NDs) are a heterogeneous group of disorders and are
considered multifactorial diseases with both genetic and environmental components …